Production moisture content

Product moisture content during spraying (dependent variable) Atomizing air volume/pressure Batch size Outlet filter shake (pulse) interval/time... 

Scale-Up Considerations Product Moisture Content During... 

Moisture. As anticipated, moisture contents of the powder samples decreased with decreasing temperature differentials between inlet and exit air temperatures when either inlet or exit air temperature was held constant (Figure 2). The sample with the highest temperature differential ( T=120 C) and lowest exit air temperature (T=80 C) had the highest moisture content (7.8%) of all the powder samples. The role of temperature differential on product moisture content is apparent from either data series in Figure 2. While the sample dried at 280 C inlet and 105 C exit air temperatures had the greatest temperature differential, the... 

Chamber inlet temperature Feed rate and thus product rate, particle size (b), product moisture content, chamber wall build-up (a) bulk density (b)... 

For stable lattices bulk density particle size and thus product moisture content chamber wall build-up... 

Chamber inlet gas humidity product moisture content, chamber wall build-up (a) ... 

Acceptance Criteria/Rationale. The acceptance criteria for each measurable attribute (which can be lifted from the specification document) is important and should always be shared. Likewise, it is recommended that a rationale be provided for each criteria. For example, why must the final product moisture content be 70-80% What if it is 83% The reasoning is that it is better to consider this question before being asked by FDA during an audit, thereby avoiding a situation in which the answer provided may not be the best. 

Many industrial processes require accurate environmental control. Examples include chemical reactions and processes that are affected by atmospheric conditions biochemical reactions quality, uniformity, and standardization of certain products factors such as rate of crystallization and size of crystals product moisture content or regain deliquescence, lumping, and caking of hygroscopic materials expansion and contraction of macliines and products physical, chemical, and biological cleanliness effects of static electricity odors and fumes conditions in storage and packaging quality of painted and lacquered finishes simulation of stratosphere or space conditions and productivity and comf ort of workers. Controlled atmospheric conditions are... 

Pikal and Shah [36] studied moisture transfer from stopper to product and resulting stability implications. They found that the product moisture content increases... 

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