Process Development Critical Factors for the Application of Heterogeneous Enantioselective Catalysts

Process Development Critical Factors for the Application of (Heterogeneous) Enantioselective Catalysts 

It is useful to divide the development of a manufacturing process into different phases  

In Phases 2 and 3, not only the results of the catalyst tests (selectivity, activity, productivity, catalyst costs, etc.) but also the total product costs decide whether the catalytic route will be further developed or abandoned. 

In the final analysis, tlie choice whether a synthesis with an enantioselective catalytic step is chosen depends very often on the answers to two questions  

If we assume that enantioselective catalysis is the method of choice, the next question in the context of our treatise is Homogeneous or heterogeneous. Table 

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