Primula obconica Primin

Derivatives. Scopoletin [92-61-5] (6-methoxyumbelliferone) (38) occurs, for example, in Sokmaceae as a growth factor in plants. Primin [15121-94-5] (2-methoxy-6-pentyl-l,4-benzoquinone) is a skin irritant isolated from Primula obconica. Versicolin [438944-0]... 

Primula dermatitis can be occupational [117], but usually one sees an older housewife with a dermatitis of the fingertips and streaks and patchy eczema on the hands, face [118] (especially the eyelids) [119] and arms [9, 120]. Primula obconica (Fig. 9) is such a common contact allergen in Europe that about i.o-i.8% of persons routinely patch tested react to the causative allergen, primin (0.01% in petrolatum) as part of the European screening series [118]. The eruption may not be suspected until the positive patch test appears [118], and the nondescript pattern may suggest an endogenous cause [118]. Rarely, one sees a reaction to the plant when the patch test to primin is negative [121]. 

Geraniol 2% (fragrant geraniums [Pelargonium spp.]) Primin Primula obconica)y 0.01%... 

Primula obconica allergy appears to be decreasing in parts of western Europe (Paulsen 1998) attempts are being made to breed cultivars that have lower concentrations of primin, the major allergen. It is unclear whether other Primula species are significant allergens. 

Primin is the allergen of Primula obconica. Occupational contact dermatitis occurs mainly in florists and horticulturists. 

Primary allergen of the plant Primula obconica found in glandular hairs on the leaves and the stem. ABCD from contact with Primula Synonyms i-isopropyl-3-methyl-s-pyrazolyldimethyl carbamate Primin 2-methoxy-6-pentylbenzoquinone dimethylcarbamic acid 3-methyl-i-(i-methylethyl)-iH-pyrazol-5-yl ester isopropylmethylpyrazolyl dimethylcarbamate dimethylcarbamic acid i-isopropyl-3-methyl-pyrazol-5-yl ester dimethyl-5-(isopropyl-3-methyl-pyrazolyl)carbamate isopropyl-3-methylpyrazoi-5-yl dimethylcarbamate Isolan Saolan... 

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