Pregnancy contraindications

In the case of tinea corporis, treatment may last longer than six weeks. The treatment of onychomycosis may last up to twelve months, certainly if the toenails are involved. Caution is required in patients with impaired kidney or Hver function or hematological disorders. Also, use is contraindicated during pregnancy. 

Toxicological studies have demonstrated that there are no important problems with fluconazole. Therapeutic doses of fluconazole may cause enzyme induction in the Hver. This suggests that interactions with other dmgs cannot be excluded. The side effects are similar to those of itraconazole and include nausea, headache, and vertigo. Occasionally, increased Hver enzymes may be noted. Like itraconazole, fluconazole is contraindicated during pregnancy. 

The tetracyclines are contraindicated if the patient is known to be hypersensitive to any of the tetracyclines. Tetracyclines also are contraindicated during pregnancy because of die possibility of toxic effects to the developing fetus. The tetracyclines are classified Pregnancy Category D drag. These drug also are contraindicated... 

The fluoroquinolones are contraindicated in patients with a history of hypersensitivity to the fluoroquinolones, in children younger than 18 years, and in pregnant women (Pregnancy Category C). These drugs also are contraindicated in patients whose life-styles do not allow for adherence to the precautions regarding photosensitivity. 

The drug is contraindicated in die presence of an allergy to die drug, pregnancy (Category C), lactation, and phenylketonuria (oral form only). Linezolid is used cautiously in patients with bone marrow depression, hepatic dysfunction, renal impairment, hypertension, and hyperthyroidism. 

This drug is contraindicated in patients with known hypersensitivity to die drug and during die first trimester of pregnancy (Category B). This drug is used cautiously in patients widi blood dyscrasias, seizure disorders, and hepatic dysfunction. Safety in children (odier dian orally for amebiasis) lias not been established. 

This drug is contraindicated in known cases of hypersensitivity to spectinomycin. In addition, the drug should not be given to infants. If another sexually transmitted disease is present with gonorrhea, additional anti-infectives may be needed to eradicate the infectious processes. Safe use during pregnancy (Category B) or lactation or in children has not been established. 

Flucytosine is contraindicated in patients with known hypersensitivity to the drug. Flucytosine is used cautiously in patients with bone marrow depression and with extreme caution in those with renal impairment. The drug is also used cautiously during pregnancy (Category C) and lactation. When flucytosine and amphotericin B are administered concurrently, the risk of flucytosine toxicity is increased. 

Mebendazole is contraindicated in patients witii known hypersensitivity. Mebendazole is also contraindicated during pregnancy (Category C). The drug, like albendazole, has exhibited embryotoxic and teratogenic effects in experimental animals. Administration of mebendazole with tiie hydantoins and carbamazepine may reduce plasma levels of mebendazole. 

Thiabendazole is contraindicated in patients with known hypersensitivity. Thiabendazole is used with caution in patients with hepatic or renal disease. Thiabendazole is a Pregnancy Category C drug and is used during pregnancy only if the potential benefit outweighs the risk to the fetus. When thiabendazole is administered with the xanthine derivatives, the plasma level of the xanthine may increase to toxic levels. It is important to monitor xanthine plasma levels closely in case a dosage reduction is necessary. 

Chloroquine is contraindicated in patients with known hypersensitivity. It is a good idea to use chloroquine cautiously in patients with hepatic disease or bone marrow depression and during pregnancy. Children are very sensitive to chloroquine, and the drug should be used with extreme caution in children. 

Iodoquinol is contraindicated in patients with known hypersensitivity. Iodoquinol is used with caution in patients with thyroid disease and during pregnancy and lactation. Iodoquinol may interfere with the results of thyroid function tests. This interference not only occurs during therapy, but may last as long as 6 months after iodoquinol therapy is discontinued. 

Paromomycin is contraindicated in patients with known hypersensitivity. Paromomycin is given with caution during pregnancy. Paromomycin is used with caution in... 

The NSAIDs are contraindicated in patients with known hypersensitivity. There is a cross-sensitivity to other NSAIDs. Therefore, if a patient is allergic to one NSAID, there is an increased risk of an allergic reaction with any other NSAID. Hypersensitivity to aspirin is a contraindication for all NSAIDs. In general, the NSAIDs are contraindicated during the third trimester of pregnancy and during lactation. 

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