POU domain proteins

Treacy, M. N He, X., and Rosenfeld, M. G. (1991). I-POU a POU-domain protein that inhibits neuron-specific gene activation. Nature 350 577-584. 

PMCA plasma-membrane Ca2+ pump SCIP suppressed cyclic AMP-inducible POU domain protein... 

Ruvkun, G., and M. Finney, Regulation of transcription and cell identity by POU domain proteins. Cell 64 475-478, 1991. 

CAR and PXR also interact with POU domain proteins such as Pit-1 and Oct-1 [61]. The interactions between Pit-1 and nuclear receptors are ligand dependent, and helix 12 in AF-2 domain of receptors is involved. In the absence of a receptor ligand, Pit-1 inhibits PXR and CAR heterodimer formation with RXR. The POU domain proteins repression of PXR and CAR may involve HDAC. Conversely, CAR and PXR repress Pit-1 by competing for coactivators [61], POU domain proteins interact... 

Sturm RA, Das G, Herr W. The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain. Genes Dev. 1988 2 15. Hum Pathol. 2005 36 10-15. 

Figure 9.13 The DNA-binding region of the protein Oct-1, the POU region (green), comprises two domains, the POU-specific domain (dark green) and the POU homeodomain (light green) joined by a linker region (blue). These two domains bind to DNA in a tandem arrangement.

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