Polymeric/polymers scaffolds

Polymerization of modified monomers makes the polymerization itself more challenging, as polymerization parameters known for common monomers, such as copolymerization reaction rates, do not necessarily apply to pre-modified monomers. Post-polymerization functionahzation methods, however, enable the use of functionahties as the side-chain modifiers to a well-defined polymer backbone so that a variety of functional polymers can be produced through one single polymer scaffold. A major challenge of this method is that the modification step must be a clean... 

Recent research in polymeric biomaterials for engineermg skeletal tissues and/or soft tissues such as muscles or lungs is focused on development of three-dimensional (3D) biodegradable polymer scaffolds [ 106]. A candidate for construction of such 3D polymer scaffolds is a fiber mesh consisting of individual polymer fibers woven or knitted into 3D patterns of variable pore size [107]. 

Wong, L. Boyer, C. Jia, Z. Zareie, H.M. Davis, T.P. Bulmus, V. Synthesis of versatile thiol-reactive polymer scaffolds via RAFT polymerization. Biomacromolecules 2008, 9 (7), 1934—1944. 

Lopez-Perez PM, da Silva RMP, Sousa RA, Pashkuleva L Reis RL. Plasma-induced polymerization as a tool for surface functionalization of polymer scaffolds for bone tissue engineering an in vitro study. Acta Biomater 2010 6 3704-12. 

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