Polyethylene glycol block copolymer

Figure 4.72 The Raman and FTIR spectra of a 10 p,m fiber of a nylon 6-polyethylene glycol block copolymer. Spectra were collected at exactly the same spot on the fiber with the JYHoriba LabRam-IR microscope with Same Spot technology. [Courtesy of Jobin Yvon, Horiba Group, Edison, NJ (www.jyhoriha.com).]...

Miyamoto, S., Takaoka, K., Okada, T., Yoshikawa, H., Hashimoto, J., Suzuki, S., and Ono, K. Polylactic acid-polyethylene glycol block copolymer. A new biodegradable synthetic carrier for bone morphogenetic protein. Clin. Orthop. 333-343,1993. 

Saito N, Okada T, Horiuchi H, Murakami N, Takahashi J, Nawata M, et al. Biodegradable poly-D,L-lactic acid-polyethylene glycol block copolymers as a BMP delivery system for inducing bone. J Bone Jt Surg 2001 83 S92-8. 

Pluronic F-68 11 Polyethylene glycol-polypropylene glycol block copolymer N 29 190mg/L po, par... 

Most of the commercial polymers consist of polyether blocks separated by polyamide blocks. The polyether blocks may be based on polyethylene glycol, polypropylene glycol or, more commonly, polytetramethylene ether glycol. The polyamides are usually based on nylon 11 but may be based on nylons 6 or 66 even a copolymer, e.g. 6/11. 

VandeVondele S, Voros J, Hubbell JA (2003) Rgd-grafted poly-l-lysine-graft- (polyethylene glycol) copolymers block non-specific protein adsorption while promoting cell adhesion. Biotechnol Bioeng 82 784—790... 

Under these conditions, the polyethylene oxide blocks behave chromatographi-cally invisible and retention of the block copolymer is solely directed by the polypropylene oxide block, yielding fractions of different degrees of polymerization (m) with respect to PPO. The assignment of the peaks was based on comparison with the chromatogram of a polypropylene glycol. 

In their efforts to construct stimuli-responsive, supramolecular amphiphiles, Frechet et al. [126-129] reported the synthesis of a novel series of AB and ABA block copolymers via the Williamson ether synthesis (e.g., 47, Fig. 21). Polyethylene glycols (PEGs) of different lengths were used as the linear hydrophilic B block while polyaryl ether dendrons of different sizes were used as the hydro-phobic A block. These copolymers were characterized by optical microscopy,... 

For some examples, see e.g. (a) Hogan CF, Harris AR, Bond AM et al (2006) Electrochemical studies of porphyrin-appended dendrimers. PhysChemChemPhys 8 2058-2065 (b) Jang W-D, Nishiyama N, Zhang G-D et al (2005) Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with polyethylene glycol to enhance intracellular photodynamic efficacy. Angew Chem Int Ed 44 419 -23 (c) Loiseau F, Campagna S, Hameurlaine A et al (2005) Dendrimers made of porphyrin cores and carbazole chromophores as peripheral units. Absorption spectra, luminescence properties, and oxidation... 

Fig. 4. A block copolymer of polyethylene glycol) and polyfaspartic acid) containing adriamycin and IgG (according to Yokoyama et al. [135])...

Block copolymers consisting of polyethylene glycol and a di-peptide, (V), were prepared by Hossainy (4) and used as a drug delivery device and to treat chronic... 

In our work, we calculate the equilibrium moisture from the dry and saturated mass of samples. The method was described by Thomson. We use more hydrophilic polyols, for example, hydrophiUc polyurethanes and polyethylene glycol homopolymers are used. More commonly, however, we will be using polyols from the Pluronic series of block copolymers discussed in Chapter 2. 

Yui and coworkers prepared CD-based polyrotaxane of Type 5 by capping the cyclic on a triblock copolymer of polyethylene glycol) and polypropylene glycol) using a blocking group [92]. When the peptide linkage was between PEO and the BG, the thermal stability of the polyrotaxane was related to disassociation... 

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