Poke root

Poke root Antirheumatic Hemorrhagic gastritis Avoid... 

Poke Root, Red Clover, Sarsaparilla, Soapwort, Spikenard, Water Dock. 

Black Cohosh Poke Root Prickly Ash Agrimony Yarrow... 

Phytolacca decandra, Poke root. Alterative for other uses, see Dispensatory, 1 to 5 grs. Pulv. 2[lb.] 0[oz.]... 

Elderflower Yarrow Poke root Burdock root Clivers Poplar bark Senna leaf Uva ursi... 

Indian Remedy for Blieuxna tism. Macerate the following ingredients for a few days in 1 quart rye whiskey 1 onnee bark of waboo root, 1 ounce blood root, 2 ounces black cohosh root. 4 ounce swamp hellebore, 1 ounce prickly- asi. b rk, and 1 ounce poke root cut fine. Dose, 1 tea spoonful every 3 or 4 hours, increasing the dose os tho stomach will bear it. 

Kheumatic Decoction. Virginia snako-root, 1 drachm sarsaparilla in powder, 6 drorhm.K burdock seed. 2 drachma poke root, 2 drachms wine-pine bark, 2 dracnmB ... 

Any red root species. One species, Ceanothus thrysiflorus (California lilac), has historically been successful in the treatment of malignant diphtheria. Other alternatives cleavers, which is much milder (a food herb), poke root, which is much stronger (a drug herb) and should be used with care. 

Topically applied poke root preparations are sometimes used to treat mastitis. To avoid exposure of nursing infants to poke, such preparations should not be applied on or near the nipple (Mills and Bone 2005). 

Saponins isolated from poke root enhanced the absorption of heparin in mice by increasing the activated partial thromboplastin time (APTT) and thrombin time, modulating the transport of heparin via the intestinal route (Cho et al. 2003). 

No information on the safety of poke root during lactation was identified. While this review did not identify any concerns for use while nursing, safety has not been conclusively established, and poke root is not recommended for use except under the supervision of an expert qualified in its appropriate use. 

A 43-year-old woman developed nausea, vomiting, cramping, generalized weakness, hematemesis, bloody diarrhea, and hypotension after ingesting one cup of poke root tea ( 1 g of root) (Lewis and Smith 1979). 

Mitogenic activity of lectin compounds from poke root has been observed (Barker et al. 1965 Fames et al. 1964 Kino etal. 1995). 

One reference text indicates, with no details, that preparations of poke root have been used as abortifacients (Watt and Breyer-Brandwijk 1962). 

No information on the safety of poke root during lactation was identified. 

Cats intraperitoneally administered 1 g/kg of a hydroalcoholic extract of poke root experienced discomfort, retching, emesis, weakness of the legs, stupor, profound narcosis, and death from respiratory failure (Golstein et al. 1973). 

No acute toxic effects were observed in rats intraperitoneally administered 3.6 ml/kg of ether, chloroform, water, or Prollius fluid extract of poke root. The extracts were prepared such that 1 ml was equivalent to 1 g of dried poke root. In rats administered an alcohol extract at the same dose, catharsis and uresis occurred, followed by drowsiness, labored breathing, paralysis of the lower limbs, failure of respiration, and death (Ahmed et al. 1949). 

The LD50 of intraperitoneally administered saponins from poke root is 181 mg/kg in mice and 208 mg/kg in rats... 

Intraperitoneal administration of 0.25 ml of a saline suspension of poke root was lethal to mice (animal weight not specified) (Macht 1937). The lethal dose of the same extract in rats and guinea pigs was 5 ml/kg (Macht 1937). 

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