Physiological strain individual differences

From a physiological point of view the brains of members of the same strain are undeniably equal in their natural endowments. The device is the same. In the human, however, the extreme differences in life conditions that primarily determine the realm of the acquired drives, combined with substantial individual differences in learning ability, make unpredictable as to which trifling proportion of the immense inborn functional pool will be utilized. An individual necessarily strives to build those forms of acquired drives that demand the shortest training time with the lowest investment of energy. It is the plastic... 

Over the past 10 years, methods have been optimized for the direct analysis of individual cells, groups of cells, and small tissue sections [8-27]. Peptide profiling of complex mixtures by MALDI TOP MS has been performed without previous molecular separation to show differences between cell types and physiological conditions, identify novel peptides, assess post-translational processing, and demonstrate peptide localization within the tissues. Additional experiments have demonstrated sub-cellular protein localization within intact cells [23,28]. Efforts have also been made to characterize bacterial strains based on intact peptide and protein profiles [12,15,18]. Most of this early work involved analysis of peptides and low-molecular-weight proteins, typically from established cell lines. 

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