Physiological properties and

Tyler, V.E. The physiological properties and chemical constituents of some habitforming plants. Lloydia 1966 29 275. 

Coe, N.R. and Bernlohr, D.A. (1998) Physiological properties and functions of intracellular fatty acid-binding proteins. Biochimica et Biophysica Acta 1391, 287-306. 

Sakai K. 1991. Physiological properties and afferent connections of the locus coeruleus and adjacent tegmental neurons involved in the generation of paradoxical sleep in the cat. Prog Brain Res 88 31-45. 

TABLE 10.2. Physiological properties and disposition of antibodies and serum albumin in humans... 

It is interesting to note that various QSAR/QSPR models from an array of methods can be very different in both complexity and predictivity. For example, a simple QSPR equation with three parameters can predict logP within one unit of measured values (43) while a complex hybrid mixture discriminant analysis-random forest model with 31 computed descriptors can only predict the volume of distribution of drugs in humans within about twofolds of experimental values (44). The volume of distribution is a more complex property than partition coefficient. The former is a physiological property and has a much higher uncertainty in its experimental measurements while logP is a much simpler physicochemical property and can be measured more accurately. These and other factors can dictate whether a good predictive model can be built. 

Physiological Properties and Purification of an Inducible Malic Enzyme, J. Bacteriol. (1969) 98, 705-711. 

Benzylated 1,2,3,4-tetrahydroisoquinolines possess important physiological properties and, as illustrated in Scheme 20, also serve as common intermediates for synthesis of naturally ubiquitous isoquinoline alkaloids with different skeletons. Because some natural products have the 1/ configuration while the others possess the IS configuration, the synthesis must be chirally flexible. 

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