Photodynamic therapy applications

Chou, T.M. et al. (2002) Photodynamic therapy applications in atherosclerotic vascular disease with motexafin lutetium, Catheterization and cardiovascular interventions official journal of the Society for Cardiac Angiography Interventions 57, 387-394. 

Dougherty, T. J. (2002). An update on photodynamic therapy applications Journal of Clinical Laser Medicine Surgery 20 3-7. 

S. L. Marcus, in C. J. Corner, ed., Euture Directions and Applications in Photodynamic Therapy, SPIE, Bellingham, Wash., 1990, pp. 5ff... 

Investigations of the kinetics of hole transfer in DNA by means of pulse radiolysis of synthetic ODNs have provided details about the hole transfer process, especially over 1 /is, including the multi-step hole transfer process. Based on the investigation of the kinetics of hole transfer in DNA, development of the DNA nanoelectronic devices is now expected. An active application of the hole transfer process is also desirable from a therapeutical point of view, since hole transfer may play a role in improvement of quantum yield and selectivity of DNA scission during photodynamic therapy. The kinetics of the hole transfer process is now being revealed, although there is still much research to be performed in this area. The kinetics of adenine hopping is another area of interest that should be explored in the future. 

The most important application for singlet oxygen generators (SOGs), namely the anti-cancer treatment known as photodynamic therapy (PDT), is described elsewhere in this series (see Chapter 9.22). However, SOGs are also being evaluated in other areas, such as hard surface disinfectants, soaps and washing powders,73 and insecticides.74,75... 

Over the past 20 years, the principal biomedical application for (free or metal-substituted) porphyrins has been Photodynamic Therapy (PDT), with extensive literature in the area including a number of comprehensive reviews (114-116). Porphyrins offer scope for optical imaging as they are potent fluorophores in the red region of the electromagnetic spectrum. Although, to date, the emphasis has been on their therapeutic effects, due to their... 

Dye-doped polymeric beads are commonly employed in different formats (Fig. 5), namely as water-dispersible nanosensors, labels and in composite materials (DLR-referenced and multianalyte sensors, sensor arrays, magnetic materials, etc.). The sensing properties of the dye-doped beads are of little or no relevance in some more specific materials, e.g., the beads intended for photodynamic therapy (PDT). The different formats and applications of the beads will be discussed in more detail in the following section, and the relative examples of sensing materials will be given. 

Harrod-Kim P (2006) Tumor ablation with photodynamic therapy introduction to mechanism and clinical applications. Journal of Vascular and Interventional Radiology 17 1441-1448. 

In recent years dye lasers operating in the spectral region of 600-750 mn have been of particular interest as they have found applications in photodynamic therapy of... 

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