Phosphorus trichloride oxide

The reaction with oxygen converts phosphorus trichloride to phosphorus trichloride oxide (oxychloride), POCI3 the trichloride is able to remove oxygen from some molecules, for example sulphur trioxide... 

Phosphorus pentachloride sublimes and then dissociates on heating, dissociation being complete at 600 K. It is attacked by water, yielding first phosphorus trichloride oxide, thus ... 

Oxidation of trichloride produces phosphorus trichloride oxide which may be used as the starting material to prepare alkyl-and alkoxyphosphine oxides ... 

PCI3O] phosphoryl trichloride, or phosphorus trichloride oxide phosphoryl trichloride trichloridooxidophosphorus... 

NiSe1,05 NICKEL 1.05-SELENIDE 1224 POCI3 PHOSPHORUS TRICHLORIDE OXIDE 1266... 

NiSe1.143 NICKEL 1.143-SELENIDE 1224 POCI3[g] PHOSPHORUS TRICHLORIDE OXIDE (GAS) 1267... 

Phosphorus trichloride oxide (phosphoryl chloride), POCI3 [10025-87-3] is obtained by oxidising PCI3 with air or oxygen. 

Hydroxylamine Barium oxide and peroxide, carbonyls, chlorine, copper(II) sulfate, dichromates, lead dioxide, phosphorus trichloride and pentachloride, permanganates, pyridine, sodium, zinc... 

Organophosphorus Derivatives. Neopentyl glycol treated with pyridine and phosphorus trichloride in anhydrous dioxane yields the cycHc hydrogen phosphite, 5,5-dimethyl-l,3-dioxaphosphorinane 2-oxide (2) (32,33). Compounds of this type maybe useful as flameproofing plasticizers, stabilizers, synthetic lubricants, oil additives, pesticides, or intermediates for the preparation of other organophosphoms compounds (see Flame retardants Phosphorus compounds). 

The A -oxide reactions in quinazoline 3-oxide are, however, modified to a certain extent by the aforementioned properties. Thus, whereas it can be reduced to quinazoline with phosphorus trichloride or iron and ferrous sulfate in ethanol, reactions with alkali, acetic anhydride, and benzoyl chloride in the presence of cyanide result in ring fission (Scheme 4). 

Reduction of pyrimidine substituted quinazoline 3-oxides, cata-lytically or with phosphorus trichloride, also leads to quinazolines. ... 

Replacement of one of the benzene rings by pyridine in the fenamic acid-type analgesics leads to an agent with full pharmacologic activity. Treatment of the N-oxide of nicotinic acid with phosphorus trichloride followed by hydrolysis of the acid... 

A mixture of 3 grams (0.01 mol) of 7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2(1 H)-one 4-oxide, 30 ml of chloroform and 1 ml of phosphorus trichloride was refluxed for one hour. The reaction mixture was then poured on ice and stirred with an excess of 40% sodium hydroxide solution. The chloroform was then separated, dried with sodium sulfate, filtered and concentrated in vacuo. The residue was dissolved in methylene chloride and crystallized by the addition of petroleum ether. The product, 7-chloro-Tmethyl-5-phenyl-3H-1,4-benzodiazepin-2(1 H)-one, was recrystallized from a mixture of acetone and petroleum ether forming colorless plates melting at 125°-126°C. 

Benzodiazepinone A-oxides 7 are smoothly deoxygenated by the action of phosphorus trichloride (Method A) or by catalytic hydrogenation (Method B) to yield benzodiazepinones 8.223... 

On the other hand, phosphorous acid monoesters of lower alcohols easily undergo transesterification [75]. A preferred starting material is the triester of ethylene chlorohydrin, obtained by reaction of phosphorus trichloride with ethylene oxide, according to Eq. (28). 

Phosphorus trichloride also reacts with glycol and ethylene oxide to form other a-hydroxyalkanephosphonates, serving as additives for polyurethane and polyester plastics to make these substances flame-resistant. 

Dichloroethylphosphine has been shown to react with methyl vinyl ketone to form 2-ethyl-5-methyl-A -l,2-oxaphospholen-2-oxide (25), which has been converted to (26) by chlorination in the presence of base. The same phosphine adds to methyl acrylate in the presence of acetic acid to give the phosphine oxide (27). Further examples have appeared of the reactions of the phenylhydrazones of methyl ketones with phosphorus trichloride to produce the heterocycles (28). 

Banks, R. E. et al., J. Chem. Soc., Perkin Trans. 1, 1974, 2535-2536 During an increased-scale preparation of the dioxyl by permanganate oxidation of the hydrolysate of a nitrosotrifluoromethane-tetrafluoroethylene-phosphorus trichloride adduct, an impurity in the dioxyl, trapped out at — 96°C ( — 196°C) and <2.5 mbar, caused a violent explosion to occur when the trap content was allowed to warm up. A procedure to eliminate the hazard is detailed. 

It reacts violently in halogen-exchange and oxidation-reduction reactions. Phosphorus trichloride... 

A number of P-chirogenic diaminophosphine oxides (DIAPHOXs) 275 derived from aspartic acid were prepared via hydrolysis of triaminophosphine intermediate 274, generated in a fully diastereoselective reaction of triamines 273 with phosphorus trichloride (Scheme 65) [102, 103],... 

Phosphorus trichloride (but not the pentachloride) also reacts smoothly with ethylene oxide stepwise2 thus ... 

As already mentioned (p. 99) ethylene oxide reacts with phosphorus trichloride to give ultimately tri-(2 - chloroethyl) phosphite, P(0CH2CH2C1)3.1 In a similar manner CgHgOPC and (C6H50)2PC1 will give the corresponding mixed phosphite esters. 

The reaction vessel is attached to the high-vacuum system, and the phosphorus trichloride transferred to it without loss and without risk. Further to reduce the hazards, a powerful magnetic stirrer is employed. The ethylphosphonous dichloride is then oxidized in benzene solution in a vessel connected directly to the vacuum system. 

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