Phosphorus Chloride related reagents

Several methods for the preparation of the parent compound in this system, tris(trimethylsilyl)phosphite, have been reported.114 118 The application of this and related reagents in reaction with alkyl halides has been reported and used for the preparation of a variety of phosphonic acid analogues of phospholipids.114119-124 Interestingly, alkyl chlorides appear to be more reactive with the silyl reagents than do alkyl iodides, a reversal of the normally observed trend with alkyl esters of the phosphorus acids. (The particular use of silyl phosphorus reagents for the synthesis of biologically significant compounds has... [Pg.47]

Related Reagents. Dimethyl Sulfoxide-Acetic Anhydride Dimethyl Sulfoxide-Dicyclohexylcarbodiimide Dimethyl Sulfoxide-Methanesulfonic Anhydride Dimethyl Sulfoxide-Oxalyl Chloride Dimethyl Sulfoxide-Phosgene Dimethyl Sulfoxide-Phosphorus Pentoxide Dimethyl Sulfoxide-Sulfur Trioxide/Pyridine Dimethyl Sulfoxide-Tiifluoroacetic Anhydride Dimethyl Sulfoxide-Triphosgene. [Pg.233]

Related Reagents. A/-Chlorosuccinimide-Dimethyl Sulfide Chromic Acid Dimethyl Sulfide-Chlorine Dimethyl Sulfoxide-Acetic Anhydride Dimethyl Sulfoxide-Dicyclo-hexylcarbodiimide Dimethyl Sulfoxide-Oxalyl Chloride Dimethyl Sulfoxide-Phosphorus Pentoxide Dimethyl Sulfoxide-Sulfur Trioxide/Pyridine Dimethyl Sulfoxide-Trifluoroacetic Anhydride Dimethyl Sulfoxide-Triphosgene Manganese Dioxide Pyridinium Chlorochromate Pyridinium Dichromate Ruthenium(rV) Oxide Silver(I) Carbonate on Celite 1,1,1-Triacetoxy-1,1-dihydro-1,2-benziodoxol-3( 1 H)-ons. [Pg.234]

Related Reagents. Dimethylchloromethyleneammonium Chloride Oxalyl Chloride Phosphorus(III) Chloride Phos-phorus(V) Oxide Phosphorus Oxychloride Thionyl Chloride Triphenylphosphine-Carbon Tetrachloride Triphenylphosphine Dichloride. [Pg.337]

Related Reagents. Bis(trichloromethyl) Carbonate Phos-phorus(V) Oxide Phosphorus Oxychloride-Zinc(II) Chloride Thionyl Chloride p-Tolyl Vinyl Sulfoxide Trichloromethyl Chloroformate. [Pg.349]

Related Reagents. Aluminum Chloride Diphenylsilane-Tetrakis(triphenylphosphine)palladium(0)-Zinc Chloride Phos-phorus(in) Chloride-Zinc(II) Chloride Phosphorus Oxychlo-ride-Zinc(II) Chloride Tin(rV) Chloride Tin(IV) Chloride-Zinc Chloride Titanium(IV) Chloride Zinc Bromide. [Pg.477]

Much the same activity is retained when the nitrogen atoms in the heterocyclic nucleus are shifted around. The convergent scheme to this related compound starts with the acylation of alanine (35-1) with butyryl chloride (35-2). The thus-produced amide (35-3) is then again acylated, this time with the half-acid chloride from ethyl oxalate in the presence of DMAP and pyridine to afford the intermediate (35-4). In the second arm of the scheme, the benzonitrile (35-5) is reacted with the aluminate (35-6), itself prepared from trimethyl aluminum and ammonium chloride, to form the imidate (35-7). Treatment of this intermediate with hydrazine leads to the replacement of one of the imidate nitrogen atoms by the reagent by an addition-elimination sequence to form (35-8). Condensation of this product with (35-4) leads to the formation of the triazine (35-9). Phosphorus oxychloride then closes the second ring... [Pg.599]

Further relation between the hydroxyl groups was discovered by Orekhov and his co-workers (39, 40). When platynecine was treated with a variety of reagents (sulfuric acid, thionyl chloride, phosphorus trichloride, phosphorus pentachloride, or phosphorus oxychloride), it underwent the loss of a molecule of water to form anhydroplatynecine, CgHisNO, b.p. [Pg.127]

In related work, solid-phase-mediated synthesis of isonitriles from formamides was achieved by using polystyrene-bound sulfonyl chloride as a suitable supported reagent [115]. The sulfonyl chloride resin could be quantitatively regenerated by treatment of the sulfonic acid resin formed with phosphorus pentachloride (PCI5) in N,N-dimethy]formamide at room temperature. [Pg.773]