Phenyl 2,2 -bipyridyl

There are few examples of luminescent metallo-intercalators which can simultaneously act as emission probes of nucleic acid structure and display promising anticancer activities. A luminescent platinum(ii) complex, [Pt(C N N)(C=NtBu)]Cl04 (HC N N = 6-phenyl-2,2 -bipyridyl), that intercalates between the nucleobases of nucleic acids accompanied by an increase in emission intensity and/or a significant change in the maximum emission wavelength, has been reported. This new species forms an emissive exciplex with double-stranded DNA with resulting photoinduced DNA damage. 

Numerous other complexes of beryllium with organic ligands such as alloxides (276-280), /6-diketonates (90, 281-297), SchifF bases (64, 298-301), thiols (302), pyridines (303), bipyridyl (304), phthalocya-nine (305), hydroxyquinolines (306, 307), tropolones (308, 309), pyra-zolylborates, (94, 310), phosphinates (311), hydrazides (312), phenyl-hydrazonocarboxylates (313), dinaphthofuchsonedicarboxylates (314),... 

Other mixed-valence metal complexes have been published that display electrochromic behavior, among them bipyridyl ruthenium complexes linked through dioxolene containing bridging ligands, such as 3,3, 4,4 -tetrahydroxybi-phenyl, 3,3",4,4"-tetrahydroxy-p-terphenyl, and 9-phenyl-2,3,7-trihydoxy-6-flu-orone [115,116] (Chart 3). Many of the redox processes that lead to frequently... 

Photolysis of aryl or pyridyl oxime esters in pyridine provides a-phenylpyridines as the major products together with bipyridyls (84TL3887). Rate constants for the addition of phenyl radical to protonated and non-protonated 4-substituted pyridines have been determined by studing the competition between phenyl radical addition and chlorine abstraction from carbon. The 4-arylpyridines were the major products, and no 3-substituted pyridines were observed. Among the solvents studied (MeCN, DMF, DMSO, and HMPA), MeCN gave the highest yields and selectivity (910PP438). 

Fumkawa, N. Shibutani, T. Fujihara, H. Preparation of bipyridyl derivatives via a-lithiation of pyridyl phenyl sulfoxides, substitution with electrophiles and cross-coupling reactions with Grignard reagents. Tetrahedron Lett. 1989, 30, 7091-7094. 

Recently, [Ruin(amp)(bipy)H20]Cl-2H20, where H2amp is N-(hydroxy-phenyl) salicyldiimine and bipy is 2,2 -bipyridyl, was reported to show remarkably high catalytic activity, using tm-BuOOH as the oxidant, for the oxidation of benzene to phenol and benzoquinones [36-38] (Fig. 8). 

A 50-ml Schlenck tube equipped with a stirring bar containing bis(l,5-cyclooc-tadiene)-nickel(O) (4.48 mmol), 2,2 -bipyridyl (4.48 mmol), and 1,5-cycloocta-diene (4.48 mmol) was treated with 5 ml of DMF and the ensuing deep blue/ purple solution stirred at 60°C for 30 minutes. The mixture was then treated with 2,7-diiodo-9,9-bis(2-ethylhexyl)fluorene (1.68 mmol) and 2,5-bis(p-bromo-phenyl)-A-(p-hexylphenyl)pyrrole (0.56 mmol) in 20 ml of toluene by syringe and then stirred for 5 days at 75°C. The solution was cooled to ambient temperature and precipitated into a mixture of 100 ml apiece of methanol and acetone and 5 ml concentrated hydrochloric acid. After of the mixture was stirred for 2 hours, it was filtered the solid residue was dissolved in chloroform and re-precipitated in methanol and acetone solution, and re-filtered. The residue was successively washed with methanol, water and methanol, and dried the product was isolated having a Mj, of 47,200 daltons. 

Pseudo polyrotaxanes consist of low molecular weight rotaxanes which can assemble via non-covalent interactions. An illustrative example has recently been described by Stoddart, using a tetra-cationic bis(bipyridyl-phenyl)-cyclophane as macrocyclic ring component and phenylene-l,4-bis(oxy-oligoethyleneoxy)-co-carboxylic acid [385]. 

Finally, a compound formed by dissolving chromium trioxide and 2,2-bipyridyl in glacial acetic acid saturated with dry hydrogen chloride has been reported to cleave double bonds without complicating side reactions. Unfortunately this oxidant, which is reported to have the formula of (bipy)H2CrOCl5, is effective only with phenyl-substituted double bonds. 

The reaction of [MoBr2(CO)4] with the DPT anion (DPT = 2,6-di-phenylthiophenolate) differs from that with other 2,6-substituted aromatic thiolates. The stoichiometry [Mo(DTP)2(CO)] of the product initially suggested three coordination however, spectroscopic studies and an X-ray crystal structure revealed that one of the 2,6-phenyl groups is 7j -bonded to the molybdenum (Fig. 6). The 7j -arene ligand is labile and can be reversibly replaced by three CO ligands. Replacement of this ligand also occurs with 2,2 -bipyridyl (bipy), 1,10-phenanthroline... 

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