Phase diagram, ternary, methanol

Experimental phase diagrams of CO2 with ethyl acetate [37] and alkyl carbonates [38] are also available. Molecular simulations that describe the binary phases diagrams of many organic solvents with CO2 were also recently published [39], Binary phase diagrams of methanol with fluoroform are also available [40], At any given pressure and temperature, fluoroform is more miscible with methanol than CO2. Ternary phase diagrams for a number of systems are also available, such as methanol/H20/C02 [41] acetonitrile/H20/C02, and methanol/H20/fluoroform [40]. 

Figure 25 shows the ternary phase diagram (solubility isotherm) for an unsolvated racemic compound. Examples of this type include benzylidenecamphor in methanol, or /V-acetylvaline in acetone [141]. In Fig. 25, A and A represent the...

Chapter 18 - The determination region of solubility of methanol with gasoline of high aromatic content was investigated experimentally at temperature of 288.2 K. A type 1 liquid-liquid phase diagram was obtained for this ternary system. These results were correlated simultaneously by the UNIQUAC model. By application of this model and the experimental data the values of the interaction parameters between each pair of components in the system were determined. This revealed that the root mean square deviation (RMSD) between the observed and calculated mole percents was 3.57% for methylcyclohexane + methanol + ethylbenzene. The mutual solubility of methylcyclohexane and ethylbenzene was also demostrated by the addition of methanol at 288.2 K. 

Figure 10. Ternary phase diagram at 298°K for systems of methanol in triolein with surfactant systems of bis(2-ethylhexyl) sodium sulfosuccinate, triethylammonium linoleate and tetradecyldimethylammonimum linoleate with 4/1 molar ratios of 2-octanol as co-surfactant.

The ternary solubility phase diagram of (S) - and (R) - propranolol hydrochloride in a mixed solvent of methanol and acetone was measured by isothermal method [25]. For isothermal method, enough amount of powder, namely lOfttO.lmg, was dissolved in the solvent of methanol in a test tube. Saturated solution samples were carefully withdrawn and filtered, and the concentration of which were analyzed by the HPLC system with employment of above-mentioned self-packed column. 

Figure 10 is a ternary diagram for the systems Triolein/S/ Methanol, where S is respectively 4/1 molar ratios of 2-octanol to bis(2-ethylhexyl) sodium sulfosuccinate, triethylammonium linoleate or tetradecyldimethyl ammonium linoleate at 25°C. Not much difference is noted between phase areas for the triethylammonium linoleate and bis(2-ethylhexyl) sodium sulfosuccinate systems. Both are definitely inferior to the tetradecyldimethylammonium linoleate which shows the greatest solubilized area of methanol in triolein at 25°C. 

Figure 3.4 shows the water-methanol mobile phase example of a mixture problem. A three-component mixture that must add up to 100% can be represented on a triangular graph, also called a ternary or trilinear diagram (see figure 3.5). When a system is optimized, it is important to be alert for... 

A number of other methods has been used to optimize ternary solvent systems, many of them69-71 similar to the window diagram used in GC. Only one more will be described briefly here. The authors, Schoenmakers et al.,72 have prepared what they call phase selection diagrams for several reverse phase LC separations. The solvents used for their mixtures are the same ones recommended by Snyder methanol, ACN, and THF. 

Pressure-temperature diagrams offer a useful way to depict the phase behaviour of multicomponent systems in a very condensed form. Here, they will be used to classify the phase behaviour of systems carbon dioxide-water-polar solvent, when the solvent is completely miscible with water. Unfortunately, pressure-temperature data on ternary critical points of these systems are scarcely published. Efremova and Shvarts [6,7] reported on results for such systems with methanol and ethanol as polar solvent, Wendland et al. [2,3] investigated such systems with acetone and isopropanol and Adrian et al. [4] measured critical points and phase equilibria of carbon dioxide-water-propionic acid. In addition, this work reports on the system with 1-propanol. The results can be classified into two groups. In systems behaving as described by pattern I, no four-phase equilibria are observed, whereas systems showing four-phase equilibria are designated by pattern II (cf. Figure 3). 

Fig. 1.35. Top the re.solution window diagram for the elution. strength ternary gradieni-elulion. separation of a mixture of twelve phenylurea herbicides in dependence on the initial sum of concentrations of methanol and acetonitrile in water at the start of the gradient. Ay. with the concentration ratio of aceionitrile, X = Vaccionimte/tVaccioniiriie + Vmethanoi) = 0.4 optimised for isocratic ternary mobile phases (Fig. I..34) and optimum gradient volume V(-, = 31 ml. Column and sample compounds as in Fig. 1.33. Bottom the separation of the twelve phenylurea herbicides with optimised ternary gradient from 18.6% methanol + 12.4% acetonitrile in water to 60% methanol + 40% acetonitrile in water in 73 min. Flow rate I ml/min.

Figure 8.22 shows ternary TMB-methanol-methane data at 35°C and 152 bar, conditions very similar to those used in the screening study. Several features of this diagram indicate that methane is the supercritical fluid solvent of choice for the separation of TMB from methanol. The shape of the two-phase region and the slopes of the tie lines reveal that greater than 70 wt%... 

Figure 9.13 gives a ternary diagram for the isopentane-methanol-TAME system at 4 bar. The phase equilibrium of this system is complex because of the existence of azeotropes. The UNIFAC physical property package in Aspen Plus is used to model the VLB in all units except the methanol/water column where the van Laar equations are used because of their ability to accurately match the experimental data. 

Mixtures of three miscible liquids can be represented by a ternary diagram such as the one shown below for water-methanol-ethanol mixtures. Any coordinate on this ternary diagram corresponds to a single liquid phase. 

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