Pharmacology miscellaneous

MISCELLANEOUS STRUCTURES As befits their chemical heterogenecity, the miscellaneous group of drugs in this section belong to a wide range of pharmacological classes as well. 

Due to the large number of references which appeared to be worth mentioning, it became necessary to divide this review into two parts. The present part deals mainly with pyridazines as chemotherapeutics, antithrombotics, antise-cretory and anti-ulcer agents, analgesic and anti-inflammatory agents as well as with various central nervous system stimulants and depressants. Part 2 of this review, which is planned for a future volume of this Series, will be devoted mainly to compounds which act on the cardiovascular system and to a discussion of miscellaneous additional pharmacological activities of pyridazine derivatives. 

Basic and Clinical Pharmacology > Chapter 50. Miscellaneous Antimicrobial Agents Disinfectants, Antiseptics, Sterilants > ... 

Mayer, A. M. S., Rodriguez, A. D., Berlinck, R. G. S., and Hamann, M. T. (2009). Marine pharmacology in 2005-6 Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, antiinflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action. Biochim. Biophys. Acta 5, 283-308. 

Certain types of pyrido[l,2-a]pyrimidines have aroused much interest owing to their valuable pharmacological properties. They are also used as synthetic intermediates or as additives to photographic materials and dyes. In the following sections the syntheses, reactions, physicochemical properties, and briefly the utilization of the pyrido[l,2-ci]pyrimidines are discussed. Within the individual sections the pyrido[l,2-ti]pyrimidinium salts, followed by the 2-oxo-2//-pyrido[l,2-a]pyrimidines, 4-oxo-4H-p3 rido[l,2-a]pyri-midines, 3,4-dihydro-2/7-pyrido[l,2- ]pyrimidines, 2-oxo-3,4-dihydro-2H-and 4-oxo-2,3-dihydro-47/-pyrido[l,2-a]pyrimidines, and finally miscellaneous pyrido[l,2- (]pyrimidines are dealt with. 

Mayer AMS, Hamann MT (2004) Marine Pharmacology in 2000 Marine Compounds with Antibacterial, Anticoagulant, Antifungal, Anti-Inflammatory, Antimalarial, Antiplatelet, Antituberculosis, and Antiviral Activities Affecting the Cardiovascular, Immune, and Nervous Systems and Other Miscellaneous Mechanisms of Action. Mar Biotechnol 6 37... 

Chambers HF. Protein synthesis inhibitors and miscellaneous antibacterial agents. In Branton LL, et al, eds. The Pharmacological Basis of Therapeutics. 11th ed. New York McGraw-Hill 2006. 

Numerous applications of pharmacokinetic-dynamic models incorporating a biophase (or effect) compartment for a variety of drugs that belong to miscellaneous pharmacological classes, e.g., anesthetic agents [419], opioid analgesics [420-422], barbiturates [423,424], benzodiazepines [425], antiarrhyth-mics [426], have been published. The reader can refer to a handbook [427] or recent reviews [405] for a complete list of the applications of the biophase distribution model. 

Miscellaneous Antidepressants. There are a few agents that either chemically or pharmacologically do not fit neatly into any of the... 

Sande, M.A. Mandell, G.L. Antimicrobial agents tetra-cyline, chloramphenicol, erythromycin, and miscellaneous antibacterial agents. In Pharmacological Basis of Therapeutics, 8th Ed. Gilman, A.G., Rail, T.W., Nies, A.S., Taylor, P., Eds. Pergamon Press New York, 1991 1117-1145. 

Miscellaneous The primary hazard associated with use of ethene, however, is its flammability and explosivity. Further Reading Goodman LS and Gilman A (eds.) (1975) The Pharmacological Basis of Therapeutics, 5th edn., p. 84. New York Macmillan. 

Miscellaneous antirheumatic drugs and their possible modes of action, 11. 1 Molecular aspects of the storage and uptake of catecholamines. 6. 121 Molecular mechanisms of specificity in DNA-antitumour drug interactions, 18, 1 Molecular pharmacology and therapeutic potential of thromboxane A receptor antagonists. 

Miscellaneous compounds of pharmacological interest have been shown to inhibit aromatase in vitro, including the antimalarial drug mefloquine, [138], the oral hypoglycaemic agent, tolbutamide [139], and nicotine, its metabolite cotinine, and anabasine, all of which are found in tobacco [140]. These effects probably have little clinical relevance, although the latter three compounds may account for the reduced urinary [141] and plasma [142] oestrogen concentrations found in smokers [140],... 

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