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Pharmacokinetic Studies During Pregnancy

Human pharmacokinetic studies indicate that methylmercury has a half-life in blood and the whole body of about 50 days (CDC 2005). Hair grows at about 1 cm/month with a delay of around 20 days between current blood concentration and appearance of mercury in hair (Myers et al. 2003). Thus, postnatal maternal hair can be analyzed sequentially to evaluate timing of methylmercury exposure during pregnancy. However, the potential that this affords to document critical periods of prenatal methylmercury exposure has yet to be realized. [Pg.290]

Stika CS, Andrews W, Erederiksen MC, Mercer B, Sabai B, Antal E. Steady state pharmacokinetic study of Flagyl ER in pregnant patients during the second to third trimester of pregnancy [abstract]. Clin Pharmacol Ther 2004 75 P24. [Pg.354]

Pregnancy A phase IV non-randomised open-label study of nelfinavir (NFV) in combination with 3TC /zidovudine assessed safety, tolerability and pharmacokinetics during pregnancy and post-partum [TOO ]. Amongst the 16 women enrolled, there were six mild treatment-related adverse effects and three serious ones (one of which (elevated... [Pg.426]

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Pharmacokinetics Pharmacokinetic studies

Pharmacokinetics studies during pregnancy

Pharmacokinetics studies during pregnancy

Pregnancy pharmacokinetics

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