Pesticides cutaneous exposure

Cutaneous exposure modeling This approach utilizes statistical and deterministic methods to aid in estimating the amount of pesticide deposited on the skin. One conceptual model of cutaneous exposure (Schneider et a ., 1999) divides the worker s environment into six compartments the. source, air, surface contatniiiaiit layer, outer clothing layer, inner clothing layer, and. skin. The following transport processes then characterize movement of the chemical within the environment emission, deposition, resuspension/evaporation, transfer. 

Yoshida K (1989) Cutaneous exposure of pesticide spray applicators, 1st edn. CRC Press, Boca Raton, FL... 

Misuse of various chemicals including industrial pesticides, toxic substances, and chemical warfare agents (CWAs) requires adequate personal protective equipment and immediate skin decontamination [151]. Since the time of World War 11, scientists have made a concerted effort to improve prophylactic and therapeutic interventions to counteract cutaneous exposure to CWAs [147]. To curtail dermal systemic exposure to environmental contaminants, most material safety data sheets (MSDSs) recommend either water rinsing or soap-and-water decontamination to remove chemicals from the skin surface [152, 153]. However, it is vital that the skin be washed in such a way that does not elicit the wash-in (W-I) effect [154], The W-1 effect is defined as an enhancement of percutaneous absorption elicited specifically by skin decontamination, particularly with water. It simply means that as some chemical contaminants are washed off the skin, the chemical substance may also wash into the skin and thus become more systemically bioavailable. 

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