Percutaneous aortic valves

Webb JG, Chandavimol M, Thompson CR, et al, Percutaneous aortic valve implantation retrograde from the femoral artery. Circulation 2006 I 13(6) 842—850. 

Percutaneous Valve Repair and Replacement for Mitral Regurgitation 124 Percutaneous Aortic Valve Replacement 131 Future Directions 138 References 138... 

Two percutaneous aortic valves have recently received CE Mark approval (CoreValve in May 2007 and Edwards-Sapien in September 2007) and several other valved stent designs are in development with first-in-man reports or in preclinical testing. Only the Edwards-Sapien valve is currently undergoing evaluation in a randomized multicenter clinical trial against surgery in the Elnited States. 

The prototypic percutaneous aortic valve was implanted in a 57-year-old male with calcified critical aortic stenosis who failed previous balloon valvuloplasty and was in cardiogenic shock as well as leg ischemia at the time of procedure. Following the procedure, the aortic pressure rose from a 70 mmHg systolic to 120 mm Hg with the aortic valve gradient decreased from 30 to 6 mm Hg. The calculated valve... 

Percutaneous aortic valve replacement is clearly in its early stages of development. Currently, there are a plethora of companies with various percutaneous aortic valve designs (Table 7.2) that promise to address... 

Table 7.2 Percutaneous aortic valve replacement technologies ... 

Rodes-Cabau J, Dumont E, De LaRochelliere R, et al. Feasibility and initial results of percutaneous aortic valve implantation including selection of the transfemoral or transapical approach in patients with severe aortic stenosis. Am J Cardiol 2008 Nov 1 102(9) 1240-6. 

Grube E, Schuler G, Buellesfeld L, et al. Percutaneous aortic valve replacement for severe aortic stenosis in high-risk patients using the second- and current third-generation self-expanding CoreValve prosthesis device success and 30-day clinical outcome. J Am Coll Cardiol 2007 50 69-76. 

Currently, the two most commonly used percutaneous aortic valves are the Edwards Sapien valve and the Medtronic CoreValve. The Edwards Sapien valve is a balloon-expandable valve made of a cobalt chromium frame and bovine pericardial leaflets. The Medtronic CoreValve is a self-expanding... 

Hanzel, G.S. et al.. Retrograde percutaneous aortic valve implantation for critical aortic stenosis. Catheter Cardiovasc Interv, 2005.64(3) p. 322-6. 

Low, R.I. et al. Direct flow medical percutaneous aortic valve Proof of concept. Eurointervention, 2008. 4(2) p. 256-61. 

Transendocardial injection is performed via a percutaneous femoral approach. An injection-needle catheter is advanced in retrograde fashion across the aortic valve and positioned against the... 

Cribier A, Eltchaninoff H, Bash A, et al. Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis first human case description. Circulation 2002 ... 

Webb JG, Pasupati S, Humphries K, et al. Percutaneous transarterial aortic valve replacement in selected high-risk patients with aortic stenosis. Circulation 2007 Aug 14 116(7) 755-63. 

Cribier A, Eltchaninoff H, Tron C, et al. Treatment of calcific aortic stenosis with the percutaneous heart valve mid-term follow-up from the initial feasibility studies the French experience. ] Am Coll Cardiol 2006 Mar 21 47(6) 1214-23. 

Grube E, Laborde JC, Gerckens U, etal. Percutaneous implantation of the CoreValve self-expanding valve prosthesis in high-risk patients with aortic valve disease the Siegburg first-in-man study. Circulation 2006 Oct 10 114(15) 1616-24. 

Bauer F,Eltchaninoff H andTron C (2004), Acute improvement in global and regional left ventricular systolic function after percutaneous heart valve implantation in patients with symptomatic aortic stenosis . Circulation, 110,1473-1476. 

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