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Nasal peptide delivery

J. Wang, Y. Tabata, and K. Morimoto. Aminated gelatin microspheres as a nasal delivery system for peptide drugs Evaluation of in vitro release and in vivo insulin absorption in rats. J Control Release 113 31-37 (2006). [Pg.232]

T. Kissel and U. Werner. Nasal delivery of peptides An in vitro cell culture model for the investigation of transport and metabolism in human nasal epithelium. J Control Release 53 195-203 (1998). [Pg.233]

Marttin, E., Verhoef, J. C., and Merkus, F. W. H. M. 1998. Ef cacy, safety and mechanism of cyclodextrins as absorption enhancers in nasal delivery of peptide and protein dtdgsug Target. 6 17-36. [Pg.157]

The nasal route is generating increasing interest as a route for the administration of local treatments and a cost-effective and patient-friendly alternative to injection for systemic delivery [49]. The special advantages of nasal delivery make it attractive for (i) crisis treatment where rapid onset of action is desirable (e.g., pain, migraine, panic attacks), (ii) systemic delivery of compounds that at present can only be delivered by injection (peptides/pro-proteins/vaccination), and (iii) direct targeting of the CNS (polar drugs for the treatment of CNS disorders). [Pg.370]

Since a comprehensive listing of every potential peptide and macromolecule that could be delivered nasally is not possible, this section will focus on (1) the drugs currently in use as nasal products in humans, (2) drugs currently in use as injectables in humans that will gain increased utilization if and when they can be formulated for nasal delivery, and (3) drugs that are currently in development for utilization in humans (Table 20.2). [Pg.384]

Arnold, J.J., et al. 2004. Correlation of tetradecylmaltoside induced increases in nasal peptide drug delivery with morphological changes in nasal epithelial cells. J Pharm Sci 93 2205. [Pg.388]

Ilium. L., Farraj, N.F. and Davis, S.S. (1994) Chitosan as a novel nasal delivery system for peptide drugs. Pharm. Res. 11 1186-1189. [Pg.120]

Nasal Delivery of Peptide and High-Molecular Weight Drugs... [Pg.591]

See other pages where Nasal peptide delivery is mentioned: [Pg.2701]    [Pg.497]    [Pg.508]    [Pg.604]    [Pg.2701]    [Pg.497]    [Pg.508]    [Pg.604]    [Pg.716]    [Pg.813]    [Pg.125]    [Pg.217]    [Pg.223]    [Pg.331]    [Pg.180]    [Pg.190]    [Pg.364]    [Pg.373]    [Pg.373]    [Pg.374]    [Pg.374]    [Pg.375]    [Pg.377]    [Pg.379]    [Pg.381]    [Pg.382]    [Pg.382]    [Pg.383]    [Pg.385]    [Pg.387]    [Pg.388]    [Pg.388]    [Pg.389]    [Pg.391]    [Pg.642]    [Pg.650]    [Pg.67]    [Pg.216]    [Pg.591]    [Pg.592]    [Pg.594]    [Pg.596]    [Pg.598]   
See also in sourсe #XX -- [ Pg.314 ]

See also in sourсe #XX -- [ Pg.238 ]



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