Peptic digestion

Physiologically, body stores are maintained by extracting approximately 10% of the iron provided in a balanced diet and this corresponds to 1.5 mg each day for males and slightly more for females to compensate for pregnancy and menses. The trace element is derived from food by peptic digestion and after reduction the ferrous form crosses the enterocyte to be released at the serosal pole via the ferroportin-hepcidin mechanism to be transported, by plasma transferrin, to developing red cells in the marrow for haemoglobin synthesis. At the end of their life span effete erythrocytes are removed by the reticuloendothelial system in the spleen, bone marrow and the liver. 

Suetsuna, K. (2002). Identification of antihypertensive peptides from peptic digest of the short-necked clam tapes philippinarum and the pearl oyster pinctada fucata martensii. 

A second peptide is pepsitensin, formed by peptic digestion of the substrate of renin (13). It represents an interesting type reaction similar to that of renin. Because two proteolytic enzymes, renin and pepsin, act on a protein to produce vasoconstrictor substances, the substrate must have peculiar structural properties conducive to formation of these substances when broken down. The pharmacology of pepsitensin has not been ex-... 

Deglycosylation had no marked effect on the stability of the acid carboxypeptidase. Both native and deglycosylated enzymes were stable up to 50°C and active in the presence of 4 M urea after 24 h. The molecular structures of both enzymes were not impaired by pepsin at pH 2.5 (Figure 25). These two enzymes had similarly great resistance to peptic digestion after 24h. 

Sakai, K., Ogawa, M., Takashima, H., Mizunuma, T., and Manabe, S. 1997. Peptic digestibility of proteins in different heat-treated commercial cow s milks. J. Jpn. Soc. Food Sci. Technol. 45, 330-333. 

Suetsuna, K. and Nakano, T. 2000. Identification of an antihypertensive peptide from peptic digest of wakame (Undaria pinnatifida). J. Nutr. Biochem. 11, 450-454. 

Acidic pH conditions caused the removal of dtraconyl groups from the citraconylated yeast proteins, so the environmental conditions of the stomach, i.e., pH and temperature, may cause the deacylation to occur following consumption of citraconylated proteins. This then would make lysine nutritionally available. The peptic digestibility of the citraconylated and decitraconylated yeast proteins was determined soy proteins and egg albumin were studied also for comparison. In a typical experi-... 

The derivative forms of toxins A and B were almost completely inactivated after 10 min of peptic digestion at pH 2.0, while the progenitor forms retained over 60% toxicity after an 80min treatment (Sugii et al, 1977a). Crystalline type A toxin was shown to be partially resistant to proteolysis by trypsin, retaining 25% of the potency of... 

Tabun Blood Adduct to BuChE Peptic digest of BuChE LC-MS-MS Fidder et al (2002)... 

Figure 3. Structure of the disulfide bonded peptic peptide of r hMCP-1. The structures of the peptide present in the 46 minute fraction obtained form the peptic digest of r hMCP-1 deduced from N-terminal sequencing and MALDI-TOF mass spectrometric analysis.

In addition to the use of new oils, significant advances were made in the manufacturing process. Peptic digestion of fat and the use of udder extracts soon were... 

The eflfect of peptic digestion is also very manifest on vitamin B12 binders. This is discussed in Section 6.2, where the formation of the peptic degradation products of the intrinsic factor-related and nonrelated binders is outlined. 

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