Quinidine Pentobarbital

Clinically important, potentially hazardous interactions with allopurinol, amiodarone, amobarbital, anabolic steroids, anti-thyroid agents, aprobarbital, aspirin, barbiturates, bivalirudin, butabarbital, butalbital, cimetidine, clofibrate, clopidogrel, cyclosporine, delavirdine, disulfiram, fenofibrate, fluconazole, gemfibrozil, glutethimide, imatinib, itraconazole, ketoconazole, levothyroxine, liothyronine, mephobarbital, methimazole, metronidazole, miconazole, penicillins, pentobarbital, phenobarbital, phenylbutazones, piperacillin, prednisone, primidone, propylthiouracil, quinidine, quinine, rifabutin, rifampin, rifapentine, rofecoxib, salicylates, secobarbital, sulfinpyrazone, sulfonamides, testosterone, thyroid, zileuton... 

Siegers, C.R Moller-Hartmann, W. Cholestyramine as an antidote against paracetamol-inducedhepato-and nephrotoxicity in the rat. Toxicol.Lett., 1989, 47, 179-184 [rat urine extracted metabolites] Lam, S. Malikin, G. An improved micro-scale protein precipitation procedure for HPLC assay of therapeutic drugs in serum. J.Liq.Chromatogr., 1989, 12, 1851-1872 [serum also amiodarone, aspirin, caffeine, chloramphenicol, flecainide, pentobarbital, procainamide, pyrimethamine, quinidine, theophylline, tocainide, trazodone fluorescence detection UV detection]... 

Also analyzed acebutolol, acepromazine, acetaminophen, acetazolamide, acetophenazine, albuterol, amitriptyline, amobarbital, amoxapine, antipsrrine, atenolol, atropine, azata-dine, baclofen, benzocaine, bromocriptine, brompheniramine, brotizolam, bupivacaine, buspirone, butabarbital, butalbital, caffeine, carbamazepine, cetirizine, chlorqyclizine, chlordiazepoxide, chlormezanone, chloroquine, chlorpheniramine, chlorpromazine, chlorpropamide, chlorprothixene, chlorthalidone, chlorzoxazone, cimetidine, cisapride, clomipramine, clonazepam, clonidine, clozapine, cocaine, codeine, colchicine, qyclizine, (yclo-benzaprine, dantrolene, desipramine, diazepam, diclofenac, diflunisal, diltiazem, diphenhydramine, diphenidol, dipheno late, dipyridamole, disopyramide, dobutamine, doxapram, doxepin, droperidol, encainide, ethidium bromide, ethopropazine, fenoprofen, fentanyl, flavoxate, fluoxetine, fluphenazine, flurazepam, flurbiprofen, fluvoxamine, fii-rosemide, glutethimide, glyburide, guaifenesin, haloperidol, homatropine, hydralazine, hydrochlorothiazide, hydrocodone, hydromorphone, hydro g chloroquine, hydroxyzine, ibuprofen, imipramine, indomethacin, ketoconazole, ketoprofen, ketorolac, labetalol, le-vorphanol, lidocaine, loratadine, lorazepam, lovastatin, loxapine, mazindol, mefenamic acid, meperidine, mephenytoin, mepivacaine, mesoridazine, metaproterenol, methadone, methdilazine, methocarbamol, methotrexate, methotrimeprazine, methoxamine, methyl-dopa, methylphenidate, metoclopramide, metolazone, metoprolol, metronidazole, midazolam, moclobemide, morphine, nadolol, nalbuphine, naloxone, naphazoline, naproxen, nifedipine, nizatidine, norepinephrine, nortriptyline, oxazepam, oxycodone, oxymetazo-line, paroxetine, pemoline, pentazocine, pentobarbital, pentoxifylline, perphenazine, pheniramine, phenobarbital, phenol, phenolphthalein, phentolamine, phenylbutazone, phenyltoloxamine, phenytoin, pimozide, pindolol, piroxicam, pramoxine, prazepam, prazosin, probenecid, procainamide, procaine, prochlorperazine, procyclidine, promazine, promethazine, propafenone, propantheline, propiomazine, propofol, propranolol, protriptyline, quazepam, quinidine, quinine, racemethorphan, ranitidine, remoxipride, risperidone, salicylic acid, scopolamine, secobarbital, sertraline, sotalol, spironolactone, sulfinpyrazone, sulindac, temazepam, terbutaline, terfenadine, tetracaine, theophylline, thiethyl-perazine, thiopental, thioridazine, thiothixene, timolol, tocainide, tolbutamide, tolmetin, trazodone, triamterene, triazolam, trifluoperazine, triflupromazine, trimeprazine, trimethoprim, trimipramine, verapamil, warfarin, xylometazoline, yohimbine, zopiclone... 

Extracted amoxapine, brompheniramine, chlorpheniramine, chlorpromazine, clomipramine, c5q)roheptadine, dsipramine, diphenhydramine, dothiepin, doxepin, fluoxetine, hal-operidol, imipramine, loxapine, maprotihne, meperidine, mesoridazine, methadone, metoclopramide, mianserin, moclobemide, nomifensine, nordoxepin, norfluoxetine, norpropoxyphene, northiaden, nortriptyline, pentobarbital, pheniramine, propojgrphene, propranolol, protriptyline, quinidine, quinine, sulforidazine, thioridazine, thiothixene, tranylcypromine, trazodone, trihe q)henidyl, triprolidine Nonintetfering dextromethorphan, norphetidine, pheno benzamine, prochlorperazine, trifluoperazine... 

Extracted acetaminophen, amobarbital, butabarbital, chlordiazepoxide, diazepam, eth-chlorvynol, flurazepam, glutethimide, methaqualone, methypiylon, nitrazepam, pentobarbital, phenobarbital, phenytoin, primidone, salicgrlic acid, secobarbital, theophylline Simultaneous amitriptyline, caffeine, clomipramine, codeine, desipramine, ethotoin, imip-ramine, lidocaine, mesantoin, methsuximide, nirvanol, nortriptyline, oxazepam, procainamide, phenylpropanolamine, propranolol, quinidine... 

Extracted metabolites, ethosxiximide, primidone, phenobarbital, phenytoin Simultaneous acetaminophen, N-acetylprocainamide, aspirin, ampicillin, caffeine, ce-phapirin, chloramphenicol, digoxin, disopyramide, hexobarbital, indomethacin, lidocaine, mephobarbital, methsuximide, nafcillin, pentobarbital, phenylethylmalonamide, procainamide, quinidine, salicylic acid, secobarbital, sulfamerazine, sulfamethazine, terbutaline, tetracycline, theobromine, theophylline... 

Simultaneous amitriptyline, amobarbital, butalbital, carbamazepine, chlordiazepoxide, chlorpromazine, clonazepam, demoxepam, desipramine, diazepam, ethinamate, fluraze-pam, glutethimide, heptobarbital, hexobarbital, lidocaine, medazepam, meperidine, mephobarbital, mesoridazine, methaqualone, pentathal, nortriptyline, oxazepam, pentobarbital, perphenazine, phenytoin, promazine, propranolol, protriptyline, quinidine, secobarbital... 

Simultaneous acetaminophen, acetophenazine, amoxapine, amphetamine, atropine, ben-peridol, buspirone, caffeine, carbamazepine, chlorpheniramine, codeine, dextromethorphan, diazepam, diphenhydramine, flupenthixol, flurazepam, heiloperidol, hydergine, hy-drocodone, hydromorphone, lidocaine, loxapine, mepazine, meperidine, mesoridazine, methaquaalude, 3,4-methylenedioxyamphetamine, 3,4-methylenedio30 ethylamphetam-ine, 3,4-methylenedioxymethamphetamine, morphine, norcocaine, oxazepam, pentobarbital, phenylpropanolamine, procainamide, procaine, propyl benzoylecgonine, quinidine, quinine, salicylic acid, secobarbital, theophylline, trazodone, 3-tropanyl-3,5-dichloroben-zoate, vancomycin, WIN 35428... 

Lurie, I.S. Demchuk, S.M. Optimization of a reverse phase ion-pair chromatographic separation for drugs of forensic interest. I. Variables affecting capacity factors. J.Liq.Chromatogn, 1981, 4, 337-355 [acetylcodeine, acetylmorphine, aminopyrene, aminopyrine, amobarbital, antipyrine, butabarbital, diamorphine, methapyrilene, morphine, narcotine, papaverine, pentobarbital, phenobarbital, quinidine, quinine, secobarbital, strychnine, thebaine]... 

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