Pentafluorobenzyl alcohol

Polyfluorobenzyl alcohols are one class of fluorinated starting materials for medicinal and agricultural usage. Practical electrochemical methods for the product-selective synthesis of polyfluorobenzyl alcohols have been developed [79, 80], 2,3,4,5,6-Pentafluorobenzoic acid is reduced selectively to 2,3,4,5,6-pentafluorobenzyl alcohol at amalgamated lead, zinc and cadmium cathodes in aqueous sulfuric acid solutions, while 2,3,5,6-tetrafluorobenzyl alcohol can also be obtained selectively by using the non-amalgamated cathodes in solutions containing small amounts of a quartemary ammonium salt [79],... 

Similarly, pentafluorobenzyl alcohol gives a high yield of l,2,3,4,5-pentafluoro-6-(fluoro-methyl)bcnzcnc (5).46... 

FLUORINECOMPOUNDS,ORGANIC - FLUORINATED AROMATIC COMPOUNDS] (Volll) Pentafluorobenzyl alcohol [440-60-8]... 

Product distributions have been determined for electrolyses of pentafluorobenzaldehyde, pentafluorobenzoic acid, and pentafluorobenzamide at mercury in aqueous media containing either sulfuric acid or TEABF4 [204]. Reduction of the aldehyde gives pentafluoro-benzyl alcohol and 2,3,5,6-tetrafluorobenzyl alcohol. Pentafluorobenzoic acid is initially converted to a mixture of 2,3,5,6-tetrafluorobenzoic acid (73%), pentafluorobenzyl alcohol (6%), and 2,3,5,6-tetrafluorobenzyl alcohol (20%) however, at a more negative potential, only the last two products are obtained in a 1 2 ratio. Pentafluorobenzaldehyde and... 

A mixture of pentafluorobenzyl alcohol and methane (1 1) for a range of airborne alkanoic acids, and phenols (Chien et al. 1998) ... 

Information for acertain parameter not available, if not given, na, not available DI, deionized water Cl, chemical ionization BCD, electron capture detector El, electron impact ionization FID, flame ionization detector MS, mass spectrometer MtBE, methyl tert-butylether MTBSTE, n-(tert-butyldimethylsilyl)-Wmethylfluoracetamide PDAM, 1-pyrenyldiazomethane PFBBr, pentafluorobenzyl bromide PEBOH, pentafluorobenzyl alcohol SPME, solid-phase microextraction TOPO, tri-n-octylphoshine oxide UASB, upflow anaerobic sludge blanket reactor. 

Pentafluorobenzyl bromide has been used in the derivatization of mercaptans [55] and phenols [36], m the analysis of prostaglandins [37], and in quantitative GC-MS [5S] 1,3 Dichlorotetrafluoroacetone is used for the derivatization of amino acids to the corresponding cyclic oxazolidinones and allows the rapid analysis of all 20 protein ammo acids [d] Pentafluorophenyldialkylchlorosilane derivatives have facilitated the gas chromatographic analysis of a wide range of functionally substituted organic compounds, including steroids, alcohols, phenols, amines, carboxylic acids, and chlorohydrms [4]... 

Chau and Terry [146] reported the formation of penta-fluorobenzyl derivatives of ten herbicidal acids including 4-chloro-2-methyl-phenoxy acetic acid [145]. They found that 5h was an optimum reaction time at room temperature with pentafluorobenzyl bromide in the presence of potassium carbonate solution. Agemian and Chau [147] studied the residue analysis of 4-chloro-2-methyl phenoxy acetic acid and 4-chloro-2-methyl phenoxy butyric acid from water samples by making the pentafluorobenzyl derivatives. Bromination [148], nitrification [149] and esterification with halogenated alcohol [145] have also been used to study the residue analysis of 4-chloro-2-methyl phenoxy acetic acid and 4-chloro-2-methyl phenoxybutyric acid. Recently pentafluorobenzyl derivatives of phenols and carboxylic acids were prepared for detection by electron capture at very low levels [150, 151]. Pentafluorobenzyl bromide has also been used for the analytical determination of organophosphorus pesticides [152],... 

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