2-fluoro-8-methyl

Dibenzo-l,4-oxatellurine 10,10-Dichloro-2-fluoro-8-methyl-E12b, 849 (Ar20 + TeCl4)... [Pg.1101]

An ether oxygen bound directly to a CH2F group, as in a fluoro-methyl ether, deshields the fluorine more than does a chlorine substituent (Scheme 3.19). [Pg.65]

Methyl 4,6-0-benzylidene-2-deoxy-3-C-[(ethoxyciirbonyl)-(fluoro> methyl)]-a-D-WAo-hexopyranoside... [Pg.172]

In related studies, it has been shown that a-fluorobenzylphosphonates ArCHFPO(OEt)2 (38) will undergo Wadsworth-Emmons-type olefination reactions with aldehydes and ketones [57]. 39 was prepared from benzaldehydes and HP(0) (OEt)2, which was fluorinated using diethylaminosulfur tiifluoride for example, diethyl [(3,5-dimethylphenyl)(fluoro)methyl]phosphonate (38) was formed in 91%. An 82% yield of Me 2-[(fluoro)(4-fluorophenyl)methylene]butanoate (1 1 E Z) (40) was obtained from 38 and methyl 2-oxobutanoate (Scheme 13). [Pg.710]

Similarly, pentafluorobenzyl alcohol gives a high yield of l,2,3,4,5-pentafluoro-6-(fluoro-methyl)bcnzcnc (5).46... [Pg.328]

The facile isomerization of simple alkylcarbenes by alkyl or hydride shifts is so rapid that these species cannot be conveniently studied even by laser-flash photolysis.128- 130 a-Fluori-nation of alkylcarbenes dramatically reduces the rate of rearrangements.131-134 e.g. fluoro(methyl)carbeneis sufficiently stabilized that it can be trapped by cyclopenta-1,3-diene.135 This type of insertion reaction is quite typical of a-fluorinated carbenes. oc-Fluorinated earbenes are less prone to CH insertion, generally adding stereoselectively to alkenes.136... [Pg.301]

Substituted benzyl fluorides react with sodium bcnzenethiolate yielding substituted (ben-zylsulfanyl)benzenes.1 The reactions were studied kinetically and found to be of the SN2 type.1 As expected, from the chloro-, cyano-, methoxy-, and methylbenzyl fluorides tested, 4-(fluoro-methyl)benzonitrile is the most reactive derivative. [Pg.426]

Disulfane (Bromo-chloro-fluoro-methyl)-(bromo-difluoro-methyl)- F.4. 648 (FCIBrC — SBr... [Pg.580]

Disulfane (Chloro-difluoro-methyl)-(dichloro-fluoro-methyl)- E4. 648 (FCI2C-S-C1 + F,C = S)... [Pg.582]

Diazene (Bis-[methylthio]-fluoro-methyl)-(difluoro-methyhhto-methyl)- ElOa, 676 (3H -> 3F)... [Pg.618]

Octadiene l-Acetoxy-3-fluoro-methyl-7-methyl- ElOa. 424 (OH -> F)... [Pg.694]

Nonatetraen-ale 3.7-Dime-thyl-9-(2,6-dimcthyl-6-tn fluoro-methyl-l-cyclohcxeiiy])- (F3-Retinal) ElOb, 523 (Educt)... [Pg.728]

Malondioate Methyl [5-Mcthyl-2-(1 -met hy I-1 -pheny l-et hy 1 )-cyclo-hcxylj Fluoro-methyl-ElOa. 448 (H - F)... [Pg.729]

Dieihoxyphosphonyl-difluoro-methyl)-2.3-dimethyl- ElOb,. 586 (Oxiran-Formation) 2-(Dicthoxyphosphoryl-di fluoro-methyl)-2.3-dimcthyl- F.lOb,. 586 [F,HC-PO(OR), + H,C — CO-CHfcl-CHj]... [Pg.738]

Difluoro-ethoxy-mcrhyl)-l-me-thvl- ElOa, 46 (CS - CF,) ElOb,. 246 (CS CF2) (Dilluoroimino-fluoro-methyl)-uu-decafluoro- ElOa, 671 (CN - CF = NF)... [Pg.763]

Tris-[bromo-fluoro-methyl]- EI0b2. 453 (Trimeris.)... [Pg.808]

EthoxycarbonyI-fluoro-methyl)-2-hydroxy- F.lOb,. 454 (Ketone I F-CH2-COOR)... [Pg.817]

A158 C7H4BrF3 4-bromo-(tr fluoro-methyl)benzene 4-BrC6H4CF3 H20 PY Me4NCl 0.1 - - DME/SCE 2A0 -... [Pg.250]

Reactions of 3,5-dichloro-2,4,6-trimethyl benzonitrile oxide 241 with fluoro-methyl substituted alkenes 242, bearing a chiral sulfinyl group at -position of the double bond, afford diastereoisomeric 4,5-dihydroisoxazoles 243 and 244 [180] with a stereoselectivity lower than 2 1 (Scheme 110). The authors conclude that the efficiency of allyl sulfoxides to control diastereoselectivity of 1,3-dipolar cycloadditions with nitrile oxides is lower than that of vinyl sulfoxides. [Pg.115]

Several radicals have been found to hydrolyse in aqueous solutions before decaying into final products. Chlorodifluoro- and dichloro-fluoro-methyl radicals hydrolyse very rapidly reactions (77) and (78) have tx /2 — 15 jusec (Balkas et al., 1971) and further hydrolysis... [Pg.287]

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