Pencycuron, a Phenylurea Fungicide for Rhizoctonia solani

Pencycuron induces abnormal branching of the hyphae of the sensitive strains of R. solani and its activity is fungistatic [2]. This morphological change implied that the mode of action of pencycuron would be antimicrotubular, like carbenda-zime, and thus it is classified as B4 Cell Division in the FRAC code list. However, while carbendazime inhibits yS-tubuline assembly in mitosis of R. solani, pencycuron does not act there but acts to destroy the cytoskeleton of microtubules. A clear-cut explanation of the mode of action of pencycuron is not yet available. Especially, the mechanistic elucidation as to why pencycuron acts only on quite limited strains of Anastomosis Groups of R. solani remains as an interesting theme. 

Although the compound was introduced to the market already in 1985, current turnover still achieved over 40 Mio US the major markets are Japan, Taiwan, Korea, Netherlands, Germany, France and UK. 

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Pencycuron, a Phenylurea Fungicide for Rhizoctonia solani S95 Table 16.2.1 Pot test results of the derivatives modified from urea herbicides. 

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