PCL composition

Zhang Y et al (2005) Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds. J Biomed Mater Res B Appl Biomater 72(1) 156-165... 

Figure 7.10 Surface resistivity, agglomerate area ratio A a, and nano tube length X50 as a function of the SME for PCL composites containing 0.5 wt% Nanocyl NC7000.

In summary of the above results, PPO/poly(styrene-co-p-chloro-styrene) blends may be divided into three compatibility categories depending upon the pClS composition of the copolymer as follows ... 

Zhang, Y, Ouyang, FL, Lim, C., Ramakrishna, S., and Huang, Z. (2005) Electrospinning of gelatine fibers and gelatine/PCL composite fibrous scaffolds. /. Biomed. Mater. Res. Part B Appl. Biomater., 72, 156-165. 

D., Ingram, G., and Yusa, S. (2013) Electrospun PLA PCL composites embedded with unmodified and 3-aminopropyltriethoxysilane (ASP) modified halloysite nanotubes (HNT). Appl. Phys. A Mater.. Sci. Process., 110, 433-442. 

Figure 11.5 Schematic showing IBU release process from LDH-IBU/PCL composite fibers. (Reproduced with permission from Ref [53] Copyright 2012 Elsevier.)...

The blended composites made of poly-L-lactic acid (PLLA)/poly-DL-lactic acid (PDLLA) and PLLA/PCL were compared for their mechanical properties [73]. In comparison with PLLA/PDLLA composites, PLLA/PCL composites have weaker mechanical properties, such as elastic modulus, yield strength, and ultimate strength. One approach of preparing these composites involves the use of methylene chloride solutions [73]. The mixed solution of PLA, PLLA, and PDLLA was poured into Teflon trays for vaporization of solvent. The composite laminates can be manufactured using the compression molding technique. 

Recently some biosynthetic composites have appeared, such as PCL/ periosteum composites for osteochondral defect repair. In vivo studies on cylindrical defects created in 10 rabbits showed that PCL-based biocomposites promote excellent subchondral bone regeneration. Research is currently focused on the synthesis of PCL composites, to combine the versatility of caprolactone together with the mechanical properties of other polymers. As poly(e-caprolactone) is another FDA-approved polymer, PCL-PLA copolymers are primary items of investigation. 

Mesenchymal stem cell differentiation (osteogenic) and in vitro calcification on pSi/PCL composites Fan et al. (2011)... 

Villmow T. Kretzschmar B. Potschke, V. In Influence of screw configuration and mixing conditions in twin-screw extrusion on dispersion of MWNT in PCL composites. ANTEC 2011, 2011,11, 0509. 

Zhang, Y. Z., H. W. Ouyang, C. T. Lim, S. Ramakrishna, and Z.-M. Huang (2005b). Electrospinning of gelatine fibers and gelatin/PCL composite fibrous scaffolds. Journal of Biomedical Materials Research 72B(1) 156—165. 

Figure 3. Focused combinatorial library in which PCL composition (blended with the optimal PEG-PCL polyurethane of Fig 1) is explored along with curing temperature. (16 points from 22x22 mm sample). Pattern shapes range from circular islands, to linear chains, looped chains, fully-closed rings, and twisted...

Biodegradable composites ramie fiber reinforced PLLA-PCL composite prepared by in situ polymerization process. Pofym. BuU., 61, 663-670. 

A similar composite based on the PCL/coUagen was also studied as substrate for skin tissue engineering. The results revealed that composite films of collagen/PCL composites are favorable substrates for the growth of fibroblasts and keratinocytes and provide adequate system for skin repair [40]. Multilayered polyelectrolyte films synthesized from hyaluronic acid, coUagen, and poly(ethyleneimine), were investigated for their in vitro response as chondrosarcoma cells proliferation with interestingly tunable antitumor properties [41] (Table 14.3). 

Figure 4.8 TEM images of PLA 15 wt%/v PCL composites reinforced with (a) HNTs, and...

HNT—ASP, which becomes more noticeable relative to that with unmodified 1 wt%/v HNTs. The nucleating-agent role of HNTs is proven to promote the heterogeneous nucleation of polymeric molecules, which is confirmed by the decrease of T, particularly in PLATS wt%/v HMW PCL composites embedded with 2wt%/v HNT—ASP, as opposed to PLA PCL counterpart. 

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