Pathogens - Anti-Plant

Pathogens may be administered via aerosol, direct application, or general release. In addition, pathogens may be applied to soil and become active when crops are planted. 

There is minimal potential for migration of pathogens to humans or animals. 

In order to avoid track out of material, immediately isolate an area around any liquid or solid contamination for at least 50 feet in all directions. Downwind evacuation may not be necessary. 

Clinical immunoassays (ELISA) are available as well as traditional techniques to culture and identify the pathogen. 

Efforts should be made to avoid possible off-site transport of the pathogen by personnel through the use of gloves, disposable foot covers and disposable coveralls. 

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Agroterrorism, which may involve anti-plant pests, in addition to anti-plant and anti-animal pathogens. 

It has been established that DXS catalyzes the first step in a novel biosynthetic pathway leading to isoprenoids in bacteria, algae, plant chloroplasts, and in the malaria parasite, Plasmodium falciparum. DXS is therefore a novel target for antibiotics, herbicides, or anti-malarials. Our work has contributed to an understanding of the novel biosynthetic pathway and could further open new perspectives on how to inhibit the pathway in pathogenic bacteria, protists, or weeds. 

Plants have envolved a wide array of chemical defences against pathogens. These include secondary metabolites with anti-microbial properties [57]. Some secondary metabolites are constitutively present in normally developed healthy plants, whereas others are induced by pathogen invasion [58]. The latter include phytoalexins, which are synthesized de novo after a pathogen attack [43], and phytoanticipins [59]. 

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