Passiflora coerulea

A new HP-TLC method has been applied for the quantitative analysis of flavonoids in Passiflora coerulea L. The objective of the experiments was the separation and identification of the compound(s) responsible for the anxiolytic effect of the plant. Samples were extracted with 60 per cent ethanol or refluxed three times with aqueous methanol, and the supernatants were employed for HPTLC analysis. Separation was performed on a silica layer prewashed with methanol and pretreated with 0.1 M K2HP04, the optimal mobile phase composition being ethyl acetate-formic acid-water (9 1 l,v/v). It was established that the best extraction efficacy can be achieved with 60 - 80 per cent aqueous methanol. The HPTLC technique separates 10 different flavonoids, which can be used for the authenticity test of this medicinal plant [121],... 

E. Pastene, M. Montes and M. Vega, New HPTLC method for the quantitative analysis of flavonoids in Passiflora coerulea L. J. Plan. Chromatogr.—Mod. TLC. 10 (1997) 362-367. 

Wolfman C, Viola FI, Paladini A, Dajas F, Medina JFI. (1994). Possible anxiolytic effects of chrysin, a central benzodiazepine receptor ligand isolated from Passiflora coerulea. Pharmacol Biochem Behav. 47(1) 1-4. 

Chrysin (=5,7- Dihydroxyflavone) (flavone) Widespread Passiflora coerulea (Passifloraceae), Pinus spp. (Pinaceae) HIV-1 protease (125 pM) [43]... 

Dihydroxyflavone Widespread Passiflora coerulea CKII, MLCK, PKA (CBZ-R,... 

There are a few members of the passionflower family (Passifloraceae) that have psychotropic effects. The one most studied is Pass flora incarnata, although some work has been done on Pass flora coerulea and Passiflora edulis. P. incarnata is a colorful, flowering plant with five white or lavender petals, a purple or pink corona, and five brightly colored stamen (Gruenwald et al. 1998). The parts of the plants used for medicinal effect are the whole plant or aerial parts. It is native to the mid- to southeastern United States. Passionflower has a history with Native Americans as a poultice to treat bruises, and as a tea for sedative/anxiolytic effects (Kowalchick and Hylton 1987). It is one of the most common herbs commercially available in Britain (Tyler 1994). 

---

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , ]

---