Liquid chromatography particle beam

Table 5.7 Theoretically predicted polypeptides from the trypsin digestion of S-lacto-globulin (/3LG) . Reprinted from J. Chromatogr., A, 763, Turula, V. E., Bishop, R. T., Ricker, R. D. and de Haseth, J. A., Complete structure elucidation of a globular protein by particle beam liquid chromatography-Fourier transform infrared spectrometry and electrospray liquid chromatography-mass spectrometry - Sequence and conformation of /3-lactoglobulin , 91-103, Copyright (1997), with permission from Elsevier Science...

C.J. Miles, D.R. Doerge and S. Bajic, Particle beam liquid chromatography-mass spectrometry of national pesticide survey analytes, Archives Environmental Contamination Toxicol., 22 (1992) 247-251. 

The different ways a particle beam liquid chromatography mass spectrometer can be configured reflect the versatility of the system in accommodating both the application and the availability of existing instrumentation. The system consists of these elements ... 

This technique is complementary to the thermospray technique. Relative advances of the particles beam technique over thermospray include library searchable electron impact spectra, improved reproducibility, easier use and increased predictability over a broad range of compounds. But since a particle beam requires same sample volatility, very large and polar compounds such as proteins may not provide satisfactory results using particle beam liquid chromatography-mass spectrometry. Additionally, certain classes of compounds such as preformed ions, azo dyes and complex sugars may not yield satisfactory electron impact spectra, but can be run on thermospray. In other words, both liquid chromatography-mass spectrometry techniques complement each other s limitations and the analyst may want to add both to address a broader range of samples. 

J Yinon, TL Jones, LD Betowski. Particle beam liquid chromatography electron impact mass spectrometry of dyes. J Chromatogr 482 75-85, 1989. 

D Hurtaud, B Delepine, P Sanders. Particle-beam liquid chromatography-mass spectrometry method with negative ion chemical ionization for the confirmation of oxacillin, cloxacillin and dicloxacillin residues in bovine muscle. Analyst 119 2731-2736, 1994. 

P.J. Kijak, M.G. Leadbetter, M.H. Thomas, E.A. Thomson, Confirmation of oxytetracycline, tetracycline and chlortetracycline residues in milk by particle-beam liquid chromatography-mass spectrometry, Biol. Mass Spectrom., 20 (1991) 789. 

Tinke, A.P. Van der Hoeven, R.A.M. Niessen, W.M.A. Tjaden, U.R. Van der Greet, J. Some aspects of peak broadening in particle-beam liquid-chromatography mass-spectrometry. J. Chromatogr. 1991, 554, 119-124. 

Turnipseed, S.B. Roybal, J.E. Rupp, H.S. Hurlbut, J.A. Long, A.R. Particle-beam liquid-chromatography mass-spectrometry of triphenylmethane dyes—Application to confirmation of malachite green in incurred catfish tissue. J. Chromatogr. 1995, 670, 55-62. 

Particle Beam Liquid Chromatography/Mass Spectrometry of Phenols and Their Sulfate and Glucuronide Conjugates... 

The particle beam-liquid chromatography-mass spectrometry (PB-L0-M8) of phenols (phenol, 4-nitrophenol, and 1—naphthol) and their glucuronide and sulfate conjugates in electron impact (El) and positive chemical ionization (PCI) is described. 

C. S. Creaser and J. W. Stygall, Particle beam liquid chromatography-mass spectrometry instrumentation and applications—a review. Analyst 118, 1467-1480 (1993). 

Jones and co-workers [228] used particle beam liquid chromatography coupled with a MS detector to determine styrene oligomers up to the w-18 oligomer of PS. Bryant and Semiyen [229] analysed cyclic oligomers of polybutylene terephthalate using column chromatography GPC (size exclusion), fast atom bombardment mass spectrometry, and tandem mass spectrometry (MS-MS). They obtained molecular weight distributions. 

M Careri, MT Lugari, A Mangia, P Manini, S SpagnoU. Identification of vitamin A, vitamin D and vitamin E by particle-beam liquid chromatography mass spectrometry. Fresenius J Anal Chem 351 768-776, 1995. 

Particle beam liquid chromatography mass spectrometry has been used to determine up to nl8 oligomers in polystyrene. ... 

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