Cortex parietal

Localization CNS Hippocampus (CA1, CA3, DG), septum, amygdala, raphe nuclei CNS Striatum, hippocampus (CA1), substantia nigra, globus pallidus, superior colliculi, spinal cord, raphe nuclei CNS like 5-HT1B but at lower densities. CNS Caudate putamen, parietal cortex, fronto-parietal motor cortex, olfactory tubercle, amygdala CNS Cortex, Thalamus, olfactory bulb (rat), claustrum (g-pig), hippocampus (CA3), spinal cord. 

Cingulate cortex Septal nuclei Occipital cortex Parietal cortex... 

Decreased numbers of dendritic spines and malformed spines in brain parietal cortex were observed at postnatal day 30 in rat pups whose mothers were administered 256-480 mg lead/kg/day as lead acetate in drinking water during gestation and lactation (Murray et al. 1978). PbB levels were not reported. 

The posterior parietal cortex is located posterior to the somatosensory cortex and serves as its unimodal association area. In addition to further processing of somatosensory input, information from the somatosensory cortex is integrated with visual inputs in this region. Association tracts from both the somatosensory cortex and the visual cortex terminate here. This activity is important for planning complex movements and for hand (prop-rioception)-eye (visual) coordination. 

Devoto P., Flore G., Saba P Fa M., Gessa G. (2005). Stimulation of the locus coeruleus elicits noradrenaline and dopamine release in the medial prefrontal and parietal cortex. J. Neurochem. 92, 368-74. 

The effect of LSD on cerebral blood flow was studied in the rat (Goldman et al. 1975). An intravenous injection of LSD increased blood flow to frontal and parietal cortex within 10 minutes, and to the cerebellum within 20 minutes. Increases (significant or nonsignificant) were evidenced in all brain areas assessed, except for the hippocampus, where a minor, nonsignificant reduction was noted. 

CYP19 mRNA of adult Rhesus monkey is high in the bed nucleus of the stria terminalis > medial preoptic/anterior hypothalamus > amygdala intermediate in the medial basal hypothalamus > lateral preoptic/anterior hypothalamus and low In the septum > lateral-dorsal-medial hypothalamus undetectable in cingulate and parietal cortex, hippocampus, and cerebellum (Abdelgadir et al., 1997). 

CYP2U1 mRNA most abundant in thymus and the cerebellum (Chuang et al., 2004). RT-PCR shows CYP26 mRNA in human olfactory bulb, temporal cortex, and hippocampus less in parietal cortex, medulla/pons region, and putamen (Ray et al., 1997). 

Kumari et al, (2003) 12 2 mg nicotine, subcutaneously N-Back Nicotine improved accuracy in all N-back conditions and reduced response times during the more demanding conditions of the task. Irrespective of drug condition, frontal and parietal regions were activated with increasing memory load. Nicotine, however, increased brain activation in the anterior cingulate (0-back, 1-back, 2-back), superior frontal (1-back, 2-back), and left superior parietal cortex (1-back, 2-back, 3-back), in the 3-back condition, nicotine reduced activation in the right superior parietal cortex. 

Staley et al. (2006) 16 Smokers 16 nonsmokers 5 lA-SPECT Recent abstinence t Striatum, parietal cortex, frontal cortex, anterior dngulated, temporal cortex, occipital cortex, cerebellum... 

Figure 5. Positron emission tomography shows the brain areas activated and deactivated during REM sleep when compared to waking. In the forebrain, more activated areas are principally limbic structures, while the posterior cingulate cortex, part of the prefrontal and parietal cortex, are deactivated. Modified from Hobson et al. (1998). Reprinted from NeuroReport with permission.

PARIETAL CORTEX allocating attention to >REFRONTAL CORTEX space (R)... 

---