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Pancuronium Aminophylline

Supraventricular tachycardia has been reported after 8 mg pancuronium in a patient taking aminophylline (800 mg/day) (16). [Pg.2671]

Belani KG, Anderson WW, Buckley JJ. Adverse drug interaction involving pancuronium and aminophylline. Anesth Analg 1982 61(5) 473. ... [Pg.2674]

Aminophylline appears to facilitate neuromuscular transmission, perhaps by increasing neurotransmitter release through raising cyclic AMP concentrations at the neuromuscular junction by phosphodiesterase inhibition (72). This would account for the antagonism of pancuronium-induced blockade that has been reported to occur in the presence of very high serum concentrations of theophylline (73). A similar effect should theoretically occur with other nondepolarizing relaxants. [Pg.3368]

Clinically important, potentially hazardous interactions with aminophylline, atracurium, cisatracurium, doxacurium, epinephrine, ergometrine, mivacurium, non-depolarizing muscle relaxants, oxprenolol, oxytocin, pancuronium, rapacuronium, rifampin, vecuronium, xanthines... [Pg.275]

Clinically important, potentially hazardous interactions with aluminum, aminophylline, carbamazepine, carbimazole, cyclosporine, daclizumab, diuretics, etoposide, etretinate, grapefruit juice, indomethacin, isoniazid, itraconazole, ketoconazole, licorice, live vaccines, methotrexate, naproxen, oral contraceptives, pancuronium, phenobarbital, phenytoin, rifampicin, troleandomycin... [Pg.473]

Cardiac arrhythmias can develop during the concurrent use of halothane and aminophylline but this seems less likely with isoflu-rane. One report attributes seizures to an interaction between ketamine and aminophylline. Supraventricular tachycardia occurred in a patient taking aminophylline when pancuronium was given. Isolated cases suggest that the effects of pancuronium, but not vecuronium, can be opposed by aminophylline. [Pg.105]

Marked resistance to the effects of pancuronium (but not vecuronium) was seen in one patient receiving an aminophylline infusion. Two other patients are reported to have shown a similar resistance but they had also been given hydrocortisone, which could have had a similar effect (see also Neuromuscular blockers + Corticosteroids , p.l21). These appear to be the only reports of such an interaction. [Pg.106]

Daller JA, Erstad B, Rosado L, Otto C, Putnam CW, Aminophylline antagonizes the neuromuscular blockade of pancuronium but not vecuronium. Crit Care Med 99 ) 19, 983-5. [Pg.106]

Azar I, Kumar D, Betcher AM, Resistance to pancuronium in an asthmatic patient treated with aminophylline and steroids, Can Anaesth Soc J (1982) 29, 280-2. [Pg.106]


See other pages where Pancuronium Aminophylline is mentioned: [Pg.106]    [Pg.121]   
See also in sourсe #XX -- [ Pg.105 ]




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