Panax ginseng saponins

Zierer R. (1991). Prolonged infusion of Panax ginseng saponins into the rat does not alter the chemical and kinetic profile of hormones from the posterior pituitary. J Ethnopharmacol. 34(2-3) 269-74. 

KarpagamV,SathishkumarN,Sathiyamoorthy S, Rasappan P, Shila S, Kim YJ et al (2013) Identification of BACE1 inhibitors from Panax ginseng saponins-an Insilco approach. Comput Biol Med 43 1037-1044... 

Platelet aggregating factor Panax ginseng saponins Panax notoginseng saponins Pseudorabies virus Polyovirus... 

Asafu-Adjaye, E. B. and Wong, S. K. (2003). Determination of ginsenosides (ginseng saponins) in dry root powder from Panax ginseng, Panax quinquefolius, and selected commercial products by liquid chromatography Interlaboratory study. /. AOAC Int. 86, 1112-1123. 

Dou, D.-Q., Chen, Y.-J., Liang, L.-H., Pang, F.-G., Shimizu, N., and Takeda, T. (2001). Six new dammarane-type triterpene saponins from the leaves of Panax ginseng. Chem. Pharm. Bull. 49, 442-446. 

Yahara, S., Tanaka, O., and Tetsuya, K. (1976a). Saponins of the leaves of Panax ginseng C. A. Meyer. Chem. Pharm. Bull. 24, 2204-2208. 

Kaku T, Miyata T, Uruno T, Sako I, Kinoshita A. (1975). Chemico-pharmacological studies on saponins of Panax ginseng C. A. Meyer II. Pharmacological part. Arzneimittelforschung. 25(4) 539-47. 

Salvati G, Genovesi G, Marcellini L, Paolini P, De Nuccio I, Pepe M, Re M. (1996). Effects of Panax ginseng C.A. Meyer saponins on male fertility. Panminerva Med. 38(4) 249-54. 

Ginseng saponins, i.e., dammarane-type saponins, are extracted from the root of Panax ginseng. They have been used in various formulations in oriental countries for more than 5,000 years, especially as a tonic [9]. 

Ginseng may be derived from any of several species of the genus Panax. Of these, crude preparations or extracts of Panax ginseng, the Chinese or Korean variety, and P quinquefolium, the American variety, are most often available to consumers in the United States. The active principles appear to be the triterpenoid saponin glycosides called ginsenosides or panaxosides, of which there are approximately 30 different types. It is recommended that commercial P ginseng formulations be standardized to contain 4-7% ginsenosides. 

The active principles appear to be a dozen or more triterpenoid saponin glycosides called ginsenosides or panaxosides. It is recommended that commercial Panax ginseng formulations be standardized to contain 7% ginsenosides. 

Table 3. Effects of initial /C+ concentration on the maximum content, production, productivity (Pv) and yield (against sugar) of ginseng saponin (S) and polysaccharide (P) in suspension cultures of Panax ginseng in shake flasks...

Fig. 5. Time profiles of A fresh and dry cell weights, medium sugar and SOUR, B the content and total production of ginseng saponin and C polysaccharide in fed-batch cultivation of Panax notoginseng cells in 1-1 airlift reactors. The arrow in A indicates the sucrose feeding point. The error bars in the figure indicate the standard deviations for the samples of three identical reactors. Symbols A Dark circles FW open circles DW open triangles, medium sugar dark triangles, SOUR. B Dark circles Saponin production open circles saponin content. C Dark circles Polysaccharide production open circles polysaccharide content...

Ginsenoside Rf (triterpene saponin) Panax ginseng (Araliaceae) [root] GABAA-R ligand (Muscimol displacement) high affinity site) CBZ-R APL [antitumour]... 

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