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Paediatric drugs development

Schachter AD, Ramoni MF. Paediatric drug development. Nat Rev Drug Discov 2007 6 ... [Pg.91]

A discussion paper (35132/03) on the implications of renal immaturity in neonates when investigating a medicine for paediatric use has been released for consultation. It is anticipated the PEG will finalise by 2005 the work commenced in 2002/2003 in assessing the paediatric needs in three therapeutic areas - gastroenterology, anti-HIV and pain. A very comprehensive work plan for PEG for 2004—5 attests to the importance of this area of drug development. [Pg.508]

Bax DA, Little SE, Caspar N et al (2009) Molecular and phenotypic characterisation of paediatric glioma cell lines as models for pre-cfinical drug development. PLoS One 4 e5209... [Pg.266]

To bring together industries and other relevant stakeholders to encourage the development of new drugs, optimise paediatric... [Pg.81]

Bleyer WA, Danielson MG. Oral cancer chemotherapy in paediatric patients Obstacles and potential for development and utilisation. Drugs 1999 58 SuppI 3 133-140. [Pg.92]

Drug overdose (paediatric) A 13-year retrospective study of lisinopril ingestion in children within the age range of 9 months to 5 years has been published [12 ]. Of the 296 patients, 8 (2.7%) developed hypotension (BP ranged from 55-74 mmHg systolic to 22-48 mmHg diastolic). The lowest dose of lisinopril that caused hypotension was 50 mg or 3.9 mg/kg. [Pg.282]

Hoang Thi TH, Morel S, Ayouni F, Flament MR Development and evaluation of taste-masked drug for paediatric medicines - Application to acetaminophen. Int J Pharm. 434 (1-2) 235-242, 2012. [Pg.516]

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See also in sourсe #XX -- [ Pg.209 ]



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