Oxymorphone hydrochloride

OXYMORPHONE HYDROCHLORIDE Relief of moderate to severe pain. Parenterally for preoperative medication, support of anesthesia, obstetrical analgesia, and for relief of anxiety in patients with dyspnea associated with pulmonary edema secondary to acute left ventricular dysfunction. 

OXYMORPHONE HYDROCHLORIDE Use smaller doses of oxymorphone than those recommended below for debilitated and elderly patients and those with severe liver disease. 

Natural opium alkaloids codeine phosphate hydromorphone hydrochloride morphine hydrochloride morphine sulfate oxycodone hydrochloride oxymorphone hydrochloride... 

Dose. 0.5 to 1.5 mg of oxymorphone hydrochloride given parenterally doses of 5 to 10 mg have been given by mouth. 

The rectal suppository is available in a concentration of 5 mg of oxymorphone hydrochloride in a base consisting of polyethylene glycol 1000 and polyethylene glycol 3350. 

OXYMORPHONE HYDROCHLORIDE (Numorphan injection 1 mg/mL, injection 1.5 mg/mL, suppositories 5 mg)... 

Oxymorphone hydrochloride is an opioid analgesic that relieves pain by stimulating opiate receptors in the CNS. It is indicated in the relief of moderate to severe pain. 

Perly, Pappalardo and Grassi [41, 43] have analysed the 600 MHz H-NMR spectra of morphine, nalorphine and oxymorphone hydrochlorides and obtained evidence of molecular conformation from V coupling magnitudes. 

Morphine and related drugs possessing potent narcotic analgesic properties, are used in clinical practice. A few examples belonging to this class of compounds are morphine sulphate diamorphine hydrochloride codeine dihydrocodeine phosphate hydromorphone hydrochloride hydrocodone tartrate oxymorphone hydrochloride. 

Known hypersensitivity to oxymorphone hydrochloride, morphine analogs such as codeine, or any of the other ingredients of OPANA, moderate or severe hepatic impairment and any situation where opioids are contraindicated such as patients with respiratory depression (in the absence of resuscitative equipment or in unmonitored settings), acute or severe bronchial asthma, hypercarbia, and in any patient who has or is suspected of having paralytic ileus. 

Oxymorphone is available for oral, rectal, and parenteral administration. Oxymorphone injectable (OPANA Injection ) is available in 1 mL ampoules containing 1 mg/mL oxymorphone hydrochloride. In addition, each 1 mg/mL ampule contains 8.0 mg/mL sodium chloride. pH is adjusted with hydrochloric acid. 

Absolute contraindication oxymorphone ER is contraindicated in patients with a known allergy or hypersensitivity to oxymorphone hydrochloride, morphine analogs, or other ingredients which are used in the manufacturing of oxymorphone ER [ 1 ]. 

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