Oxygen-limited growth

If oxygen limits growth and multiplication of aerobic bacteria, the adaptive value and inductive mechanism of poly(3HB) synthesis are quite similar to those outlined for nitrogen limitation. 2/H/ generated are not oxidized via elec-... 

Note that the data follow the same trends as those discussed in Figure 7 22, 7.4.8 Oxygen-Limited Growth... 

Butanediol is produced during oxygen limited growth by a fermentative pathway known as mixed acid-butanediol pathway (Figure 4) (222). The 2,3-BD pathway and the relative proportions of acetoin and butanediol serve to maintain the intracellular NAD/NADH balance in changing culture conditions. The theoretical... 

At first let us consider nonlimited and oxygen-limited growths. At the high medium recycling rates (1000 to 2000 1 h 1) the tower reactor exhibited CSTR-behavior with regard to the cell mass, X, and substrate, S, concentrations. The longitudinal concentration profiles of dissolved oxygen were nonuniform and were described by a dispersion model (2, 6) with particular... 

Dominguez H, Nezondet C, Lindley ND, Cocaign M. (1993). Modified carbon flux during oxygen limited growth of Corynebacterium glutamicum and the consequences for amino acid overproduction. Biotechnol Lett, 15, 449-454. 

The growth medium for a bioprocess should ideally provide all the requirements of the process organism in such a way that the organism grows rapidly, produces large amount of the desired product, does not degrade the final product, and is able to survive under harsh environmental conditions (such as shear forces, oxygen limitation etc). 

Aerobic The growth kinetics was described by an interacting, balanced and unstructured model characterized by phenol inhibition and oxygen limitation according to a double limiting kinetics [60, 62],... 

Iron is an essential cofactor of numerous enzymes, involved in, for instance, electron transfer and oxygen metabolism. It seems counterintuitive that the fourth most abundant element in the biosphere is in many instances the least bioavailable bioelement and therefore the limiting growth factor. The reason for this lies in the extremely low solubility of ferric iron (Fe3+) the prevailing form of iron under oxic conditions. Iron is precipitated as Fe(OH)3 with a solubility product of 10 39, which limits the aqueous concentration of ferric ion... 

Odour will return in treated slurry as a result of post treatment fermentation. The concentration of readily fermentable substrates, measured as BOD5, provide an indicator of this problem. In continuous culture without oxygen limitation the BOD5 can be described by a model derived from the Monod (13) model of microbial growth (14). The supernatant BOD5 (g/1) from treatment at 15 to 45°C, was described by equation 3 and the whole BOD5 by equations 4 and 5(15). 

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