Oxidative stress free radicals

A.J. Kowaltowski and A.E. Vercesi, Mitochondrial damage induced by conditions of oxidative stress. Free Radic. Biol. Med. 26, 463-471 (1999). 

Chandra, J., Samah, A., and Orrenius, S., 2000, Triggering and modulation of apoptosis by oxidative stress. Free Radical Biol. Med. 29 323-333. 

G12. Gutteridge, J. M., Quinlan, G. J., and Yamamoto, Y., Hypothesis Are fatty acid patterns characteristic of essential fatty acid deficiency indicative of oxidative stress Free Radic. Res. 28, 109-114(1998). 

Butterfield DA, Kanski J (2002) Methionine residue 35 is critical for the oxidative stress and neurotoxic properties of Alzheimer s amyloid beta-peptide 1-42. Peptides 23 1299-1309 Butterfield DA, Lauderback CM (2002) Lipid peroxidation and protein oxidation in Alzheimer s disease brain potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. Free Radic Biol Med 32 1050-1060 Butterfield DA, Poon HF, St Clair D, Keller JN, Pierce WM, Klein JB, Markesbery WR (2006a) Redox proteomics identification of oxidatively modified hippocampal proteins in mUd cognitive impairment Insights into the development of Alzheimer s disease. Neurobiol Dis 22(2) 223-232... 

Atherosclerosis, cancer and degenerative brain diseases may result from specific processes in an organ or a cell system and at the same time may be the result of the universal aging process. Damage to DNA by radicals may be a significant contributor to the age-dependent development of cancer (Halliwell, 1994). Diseases associated with oxidative stress, free radicals and metabolites generating free radicals in the body are listed in Table 3.7 (Stahelin, 1999). It is not yet clear, however, whether the oxidative stress is the primary cause of the diseases or whether formation of radicals is a secondary effect of tissue damage caused by the disease. 

Videla, L. A., Barros, S. B., Junqueira, V. B. Lindane-induced liver oxidative stress. Free Radic. Biol. Med 1990, 9, 169-179. 

Keywords Oxidative Stress Free radicals Cell proliferation Aging Protein degradation Apoptosis Growth arrest... 

Crawford DR, Wang Y, Schools GP, Kochheiser J, Davies KJA (1997) Down-regulation of mammalian mitochondrial RNAs during oxidative stress. Free Radic Biol Med 22 551-559 Crawford DR, Lauzon RJ, Wang Y, Mazurkiewicz J E, Schools GP, Davies KJA (1997) 16S mitochondrial ribosomal RNA degradation is associated with apoptosis. Free Radic Biol Med 22 1295-1300... 

Gopalakrishna, R., and Taken, S. (2000). Protein kinase C signaling and oxidative stress. Free Radic Biol MedlS, 1349-1361. 

Motterlini, R., Foresti, R., Bassi, R. and Green, C. J. Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Radical Biology and Medicine 28 1303-1312 2000. 

Oxidative stress free radical production in neural degeneration... 

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