Oxidative cyclopropane

The Structure of Ethylene Oxide, Cyclopropane and Related Molecules. 

Cyclopropanes have been used to test the reactivity of oxidizing enzymes. Thus, while the monooxygenase enzyme from Methylococcus capsulatus oxidizes cyclopropane 3 to cyclopropanol 4, on the other hand methylcyclopropane 1 a is oxidized to cyclopropylmethanol 5, also without ring opening, Eq. (2) [6]. 

Walsh, A. D. Structures of ethylene oxide, cyclopropane, and related molecules, Trans. Faraday Soc. 1949, 45,179-190. 

Nitrous oxide, cyclopropane, diethyl ether, halothane, enflurane, isoflurane... 

The pharmacology of nitrous oxide, cyclopropane, hal-othane, and ether is summarized in Table 16. Ether and cyclopropane are seldom used in anesthesiology. 

Summary Pharmacology of Nitrous Oxide, Cyclopropane, Halothane, and Ether... 

Electronic reflectance spectra of the Co(II)-exchanged dehydrated Type A zeolite, Co(II)A, show that the cobalt ions enter the S-II positions, where they form complexes with nitrous oxide, cyclopropane, water, and ammonia. These molecules represent ligands of increasing bond strength and, with the exception of ammonia, form reversible complexes with Co(II)A. In the case of nitrous oxide and cyclopropane, these complexes have a C3y symmetry water and ammonia complexes are tetrahedral. On a long exposure to water and ammonia, the Co(II) ions become highly coordinated to these ligands. 

To summarize the present results, Co (II) ions can be introduced into the Type A molecular sieves into the S-II type positions, where they are stable and resist both oxidation and reduction. These ions bind nitrous oxide, cyclopropane, water, and ammonia as additional ligands, their spectra being simultaneously changed in a defined fashion. The spectrochemical series of these ligands is, in the order of increasing ligand strength,... 

For phase-modulation measurements we have chosen tiis(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) perchlorate ([Ru(Ph2phn)3] ), which is highly sensitive to oxygen. This complex in silicon is also rather specific. The physiologically and medically important gases, CO2, nitrous oxide, cyclopropane,... 

Without additional reagents Oxidative cyclopropane ring opening ... 

Corey-Chaykovsky epoxidation—additive oxidation Cyclopropanation [(1 + 2) + (1 + 2)]... 

In this paper, we discuss the behavior of eight solutes at the interface between two immiscible liquids - water and hexane. Four of the solutes, methanol, ethanol, butanol and hexanol, are amphiphilic, straight chain alcohols. This choice allows us to examine systematically the interfacial activity of amphiphiles as a function of the hydrophobic chain length. The remaining four molecules, nitrous oxide, cyclopropane, isoflurane and desflurane are not amphiphilic. Even though nitrous oxide, cyclopropane and the two halogenated ethers are structurally unrelated, they, nonetheless, share an important property - all of them are clinical anesthetics. 

Acetylene, nitrous oxide, cyclopropane, and ethylene have a significant anesthetic effect. As discovered during deep-sea diving work under high pressure, the noble gases, possibly with the exception of helium, also have a mildly anesthetic or narcotic effect at high pressures. 

Yeom, H.-S., Shin, S. (2013). Au(I)-catalyzed intramolecular oxidative cyclopropanation of 1,6-enynes derived from propiolamides with diphenyl sulfoxide. Organic Biomolec-ular Chemistry, 11, 1089-1092. 

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