Other Hypervalent Iodine Compounds Used for Oxidation of Alcohols

Other Hypervalent Iodine Compounds Used for Oxidation of Alcohols 

The fluorine-containing hypervalent iodine compound 47, first described by Dess and Martin,5 finds occasional use in the oxidation of alcohols and is described in some substrates as superior than Dess-Martin periodinane.111 

The use of Dess-Matin reagent leads to partial lactonization, caused by the generation of acetic acid during the oxidation. This is avoided by the employment of compound 47, which produces water instead of acetic acid during the oxidation. 

Compound 48 is described as a hypervalent iodine compound possessing the distinctive advantages of being air-stable, non-explosive and soluble in common organic solvents.112 

It can be used for the oxidation of alcohols under experimental conditions similar to the ones employed with Dess-Martin periodinane. 

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