Organic-inorganic hybrid silica monolithic

Caffeine, theophylline Beverages CEC organic-inorganic hybrid silica monolith C18-sulfonic groups using a mobile phase containing 25 mM phosphate-borate (pH 8)-acetonitrile (40 60, v/v) UV at 254 run [105]... 

Hou C-Y, Ma J-F, Tao D-Y, Shan Y-C, Liang Z, Zhang L-H, et al. Organic—inorganic hybrid silica monolith based immobilized titanium ion affinity chromatography column for analysis of mitochondrial phosphoproteome. J Proteome Res 2010 9 4093-101. 

Scheme 10.14 Scheme ofthe organic-inorganic hybrid silica monolithic matrix formation (a) and trypsin immobilization (b) [128], Source Copyright 2008 American Chemical Society. 

Nanoporous carbon with narrow pore-size distribution can be prepared directly via a one-step nanocasting technique by carbonization of cyclodextrin-silica organic-inorganic hybrid composite.[260] The method consists of preparing a cyclodextrin-templated silica mesophase via soft chemistry, followed by direct carbonization of the occluded cyclodextrins. The nanocasting procedure provides granules (in millimeter scale) or monoliths (in centimeter scale). Cyclodextrins can be employed not only as structuredirecting templates but also as carriers for metal nanoparticle precursors. 

Figure 10.1 Types of silica-based sol-gel monoliths differing in porosity, (a) Aerogels, highly porous monoliths, (b) Xerogel, semiporous monoliths, (c) Inorganic-organic hybrid, nonporous monoliths.

There are some excellent review articles on different aspects of mesostructured materials, such as synthesis, properties, and applications. " Extensive research effort has been devoted to the exploitation of new phases (lamellar, cubic, hexagonal structures), expansion of the pore sizes (about 2-50 nm are accessible), and variable framework compositions (from pure silica, through mixed metal oxides to purely metal oxide-based frameworks, and inorganic-organic hybrid mesostructures). Another research focus is on the formation of mesostructured materials in other morphologies than powders, e.g. monolithic materials and films, which are required for a variety of applications including, but not limited to, sensors (based on piezoelectric mass balances or surface acoustic wave devices), catalyst supports, (size- and shape-selective) filtration membranes or (opto)electronic devices. The current article is focused... 

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