Organic anion transporting polypeptide superfamily

Hagenbuch, B. and Meier, P.J. (2003) The superfamily of organic anion transporting polypeptides. Biochimica et Biophysica Acta, 1609, 1-18. [Pg.313]

B. Hagenbuch, and P. J. Meier. Organic anion transporting polypeptides of the OATP/SLC21 family phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch 447 653-665... [Pg.572]

Meier-Abt, F., Mokrab, Y, and Mizuguchi, K. (2006) Organic anion transporting polypeptides of the OATP/SLCO superfamily identification of new members in nonmammalian species, comparative modeling and a potential transport mode. Journal of Membrane Biology, 208, 213-227. [Pg.108]

The drug uptake (SLC) family of transporter is the largest superfamily of transporters. This family includes 31 transporters from organic anion transporter polypeptides (OATPs), organic anion transporters (OATs), organic cation transporters (OCTs), peptide cotransporters (PEPTs), and sodium-bile acid cotransporter classes. Only OATP, OAT, OCT, and PEPT are primarily involved with the transport of drugs/xenobiotics. [Pg.16]

ABC, ATP-binding cassette transporter superfamily ASBT, apical sodium-dependent bile salt transporter BCRP, breast cancer resistance protein BSEP, bile salt export pump MDRl, multidrug resistance MRR multidrug resistance-related protein NTCP, sodium taurocholate cotransporting polypeptide OAT, organic anion transporter OCT, organic cation transporter SLC, solute-linked carrier transporter family SLCO, solute-linked carrier organic anion transporter family. [Pg.88]