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Specific organ toxicity

Solubility pH-profile Micronucleus test Organ-specific toxicity Phototoxicity... [Pg.48]

Ward, J.M., Peters, J.M., Perella, C.M. Gonzalez, F.J. (1998) Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor a-null mice. Toxicol. Pathol., 26, 240-246 Weghorst, C.M., Devor, D.E., Henneman, J.R. Ward, J.M. (1993/94) Promotion of hepatocellular foci and adenomas by di(2-ethylhexyl) phthalate and phenobarbital in C3H/HeNCr mice following exposure to N-nitrosodiethylamine at 15 days of age. Exp. Toxicol. Pathol, 45, 423-431... [Pg.147]

The disposition or localization, and in some cases metabolism, of foreign compounds may be dependent upon the characteristics of a particular tissue or organ, which may in turn affect the toxicity. There are many examples of organotropy in toxicology, but the mechanisms underlying such organ-specific toxic effects are often unknown. [Pg.166]

Ward JM, Peters JM, Perella CM, et al. 1998. Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisomeproliferator-activated receptor alpha-null mice. Toxicol Pathol 26(2)240-246. [Pg.298]

It becomes evident, that organs other than liver, such as lung (Yost 1999), kidney and intestine (Roediger and Babidge 1997 Paine 2003 Kaminsky and Zhang 2003) can also contribute to the metabolism of xenobiotics (De Kanter 1999) and partly to organ specific toxicity. [Pg.496]

Hepatotoxicity and Other Organ-Specific Toxicity Assays 26... [Pg.21]

Zurich MG, Stanzel S, Kopp-Schneider A, Prieto P, Honegger P (2013) Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. Toxicol In vitro 27(4) 1416-1424. doi 10.1016/j. tiv.2012.06.018... [Pg.473]

Krasula RW, Pernet AG. Comparison of organ-specific toxicity of temafloxacin in animals and humans. Am J Med 1991 91 38S-41S. [Pg.247]

See other pages where Specific organ toxicity is mentioned: [Pg.192]    [Pg.309]    [Pg.3]    [Pg.59]    [Pg.442]    [Pg.528]    [Pg.222]    [Pg.210]    [Pg.167]    [Pg.314]    [Pg.384]    [Pg.332]    [Pg.643]    [Pg.219]    [Pg.392]    [Pg.581]    [Pg.2192]    [Pg.2196]    [Pg.199]    [Pg.201]    [Pg.372]    [Pg.1627]    [Pg.2301]    [Pg.2754]    [Pg.26]    [Pg.27]    [Pg.203]    [Pg.353]    [Pg.353]    [Pg.56]    [Pg.22]    [Pg.471]    [Pg.294]    [Pg.622]    [Pg.186]    [Pg.182]    [Pg.351]    [Pg.484]    [Pg.169]    [Pg.27]    [Pg.28]   
See also in sourсe #XX -- [ Pg.27 , Pg.28 , Pg.29 , Pg.30 ]



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Organ specificity

Organ toxicants

Organ toxicity

Specific organ toxicity, definition

Specific target organ systemic toxicity - Repeated exposure

Specific target organ systemic toxicity - Single exposure

Toxic organics

Toxic specificity

Toxicity continued organ-specific

Toxicity, organ specific effects

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