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Oral drug administration insulin

Parenteral administration is not perceived as a problem in the context of drugs which are administered infrequently, or as a once-off dose to a patient. However, in the case of products administered frequently/daily (e.g. insulin to diabetics), non-parenteral delivery routes would be preferred. Such routes would be more convenient, less invasive, less painful and generally would achieve better patient compliance. Alternative potential delivery routes include oral, nasal, transmucosal, transdermal or pulmonary routes. Although such routes have proven possible in the context of many drugs, routine administration of biopharmaceuticals by such means has proven to be technically challenging. Obstacles encountered include their high molecular mass, their susceptibility to enzymatic inactivation and their potential to aggregate. [Pg.70]

The administration of oral hypoglycemic drugs The administration of oral hypoglycemic drugs has been associated with increased cardiovascular mortality as compared with treatment with diet alone or diet plus insulin. [Pg.315]


See other pages where Oral drug administration insulin is mentioned: [Pg.1081]    [Pg.505]    [Pg.506]    [Pg.833]    [Pg.401]    [Pg.573]    [Pg.62]    [Pg.316]    [Pg.71]    [Pg.31]    [Pg.296]    [Pg.126]    [Pg.189]    [Pg.211]    [Pg.1343]    [Pg.116]    [Pg.1445]    [Pg.505]    [Pg.506]    [Pg.400]    [Pg.1213]    [Pg.366]    [Pg.105]    [Pg.272]    [Pg.1095]    [Pg.1714]    [Pg.503]    [Pg.507]    [Pg.275]    [Pg.275]    [Pg.19]    [Pg.136]    [Pg.716]    [Pg.264]    [Pg.287]    [Pg.542]    [Pg.571]    [Pg.136]    [Pg.220]    [Pg.339]    [Pg.549]    [Pg.574]    [Pg.262]    [Pg.121]    [Pg.756]    [Pg.768]    [Pg.774]   
See also in sourсe #XX -- [ Pg.273 , Pg.286 , Pg.299 , Pg.374 ]




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