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Olopatadine

Molecular formula C21H23NO3 Molecular weight 337.41 CAS Registry No 113806-05-6, [Pg.470]

Sample preparation Condition a Bond Elut C18 SPE cartridge with 1 mL MeOH, 2 mL water, 2 mL 1% bovine serum albumin in water, and 5 mL water. Vortex 250 rL plasma, 50 pL 200 ng/mL IS in water, and 250 pL water, add to the SPE cartridge, wash with 2 mL water, elute with 1 mL MeOH. Evaporate the eluate to dr5Uiess under a stream of nitrogen, reconstitute the residue with 50 pL mobile phase, filter (0.2 pm PTFE), inject a 10 pL aliquot. [Pg.470]

Column 50 x 2 5 pm Develosil ODS HG-5 Mobile phase MeOH 10 mM acetic acid 45 55 Flow rate 0.1 Injection volume 10 [Pg.470]

Detector MS, Micromass Quattro, electrospray, ion source 120°, capillary 4.0 kV, counter current electrode 1.2 kV, cone 20 V, positive mode, coUision gas argon 0.2 Pa, collision energy 20 eV, m/z 338-165 [Pg.470]

Internal standard KF11796 ((llZ)-ll-[3-(dimethylamino)propyhdene]-6,ll-dihydro-dibenz[fe,e]oxepin-2-propionic acid) (m/z 352-247-179) (4) [Pg.470]

Olopatadine 1-2 drops in affected eye(s) two times daily at 6- to 8- hour intervals Headache... [Pg.940]

If mast cell stabilizers or multiple-action agents are not successful, a trial of a topical NSAID is appropriate. Ketorolac is the only approved topical agent for ocular itching. NSAIDs do not mask ocular infections, affect wound healing, increase intraocular pressure, or contribute to cataract formation like the topical corticosteroids. However, for allergic conjunctivitis, topical ketorolac is not as effective as olopatadine or emedas-tine in trials.15 Full efficacy of ketorolac takes up to 2 weeks.17... [Pg.941]

Levocabastine (Livostin) and olopatadine (Patanol) are ophthalmic antihistamines that can be used for allergic conjunctivitis that is often associated with allergic rhinitis. However, systemic antihistamines are usually effective for allergic conjunctivitis, making an ocular product unnecessary. They may be a logical addition to nasal glucocorticoids when ocular symptoms occur. [Pg.915]

Olanzapine (Zyprexa) Antipsychotic Olopatadine (Patanol) Antihistamine Olsalazine (Dipentum) Ulcerative colitis Omeprazole (Prilosec) Proton pump inhibitor... [Pg.43]

Nortriptyline 53 Notvasc 15 Notvir 60 Na/din 79 Nubain 50 Nystatin 53, 77 Octreotide 53 Ofloxadn 53 Ogen 33 Olopatadine 53 Olsalazine 53... [Pg.106]

Olopatadine (Patanol) [Ophthalmic Antihistamine] Uses Allergic conjunctivitis Action Hj-rec tor antagonist Dose 1—2 gtt in eye(s) bid allow 6—8 h between doses Caution [C, ] Disp Sohi SE Local irritation, HA, rhinitis EMS None OD Unlikely... [Pg.240]

Oral 12.5, 25, 50 mg tablets 25 mg capsules 25 mg chewable tablets Olopatadine (Patanol)... [Pg.369]

Pheniramine Acetate (Naphcon A) Nepafenac (Nevanac) Olopatadine (Patanol) GASTROINTESTINAL Antacids Alginic Acid +... [Pg.47]

Olopatadine (Kyowa Hakko) anti-inflammatory allergy... [Pg.25]

See other pages where Olopatadine is mentioned: [Pg.940]    [Pg.594]    [Pg.602]    [Pg.595]    [Pg.604]    [Pg.411]    [Pg.71]    [Pg.48]    [Pg.519]    [Pg.240]    [Pg.2504]    [Pg.2504]    [Pg.2504]    [Pg.2505]    [Pg.2506]    [Pg.2507]    [Pg.426]    [Pg.545]    [Pg.25]   
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See also in sourсe #XX -- [ Pg.240 ]

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See also in sourсe #XX -- [ Pg.470 ]

See also in sourсe #XX -- [ Pg.233 , Pg.237 ]



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Antihistamines olopatadine

Olopatadine hydrochloride

Patanol - Olopatadine

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