Oligosaccharide synthesis strategy

IV. Design of an Automated Solid-Phase Oligosaccharide Synthesis Strategy. 43... 

SCHEME 7.1 Solution-phase oligosaccharide synthesis strategy. 

Danishefsky has developed a solid phase oligosaccharide synthesis strategy based on glycals which are bonded to a polystyrene copolymer via silyl ether bonds and coupled to other glycals. The products were released by use of tetrabutylammonium fluoride. ... 

This extension considerably enhances flexibility in choosing strategies for oligosaccharide synthesis (compare Scheme 2). 

The challenge for developing methods for synthesizing oligosaccharides, notably for complex oligosaccharides, that can be scaled up to an industrial level is obvious, based on the use of substrates and enzymes that are available at reasonable cost and purity. Strategies for oligosaccharides synthesis include ... 

Cleavage Purification Scheme 7.1 Strategies for solid-phase oligosaccharide synthesis. 

This book covers all of the most recent (at the time of writing) developments in the field of solid support oligosaccharide synthesis. Included are chapters discussing different synthetic strategies, glycosylation protocols, the use of solid supports versus soluble polymeric supports and on-resin analytical methods. Special topics such as the formation of [3-glycosidic linkages on solid support are also discussed. 

Ziegler T (1997) Pyruvated Saccharides - Novel Strategies for Oligosaccharide Synthesis. 186 203-229... 

Pyruvated Saccharides - Novel Strategies for Oligosaccharide Synthesis... 

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