Oligosaccharide syntheses armed-disarmed strategy

Overall, the armed-disarmed strategy offers an efficient tool for the synthesis of oligosaccharides having a cis-trans glycosylation pattern.58,117 The synthesis of cis-cis-linked derivatives is also possible, but additional reprotection at the... 

In the traditional approaches of oligosaccharide synthesis, the product of a glycosylation reaction had to be isolated and it required some chemical transformation(s) to make it suitable for the next glycosylation reaction. In some of the synthetic strategies described in Section 5.4, such as in the sequential glycosylations and in the armed-disarmed glycosylations, the product of one... 

In conclusion, preliminary results confirmed the concept of using active and latent thioglycosyl donors in glycoside synthesis. The methodology is complementary to the armed and disarmed strategies [10] and should add another controllable variable in blockwise oligosaccharide syntheses. 

---