Olfactory receptor neurons Drosophila melanogaster

Stortkuhl KF, Kettler R (2001) Functional analysis of an olfactory receptor in Drosophila melanogaster. Proc Natl Acad Sci USA 98 9381-9385 Suh GS et al (2004) A single population of olfactory sensory neurons mediates an innate avoidance behaviour in Drosophila. Nature 431 854-859 van der Goes van Naters W, Carlson JR (2007) Receptors and neurons for fly odors in Drosophila. Curr Biol 17 606-612... 

Bhalerao S., Sen A., Stocker R. F. and Rodrigues V. (2003) Olfactory neurons expressing identified receptor genes project to subsets of glomeruli within the antennal lobe of Drosophila melanogaster, J. Neurobiol. 54, 577-592. 

Insect chemosensory organs have been differentially developed for taste and olfactory sensing. The contact and the distant chemosensory sensilla are responsible for nonvolatile and volatile chemical reception, respectively. The CHCs with long carbon chains are non-volatile, and therefore thought to be received by taste sensilla (Ebbs and Amrein, 2007). However, because of their insolubility in water, it was very difficult to obtain response recordings to them from taste sensilla. Success was recently obtained, however, in Drosophila melanogaster, where a male-specific CHC as a sex-pheromone inhibiting male-male courtship was found to stimulate the bitter taste receptor neuron within the... 

When each individual olfactory sensory cell should expresse only one specific receptor it would require extraordinarily strict control of gene expression. For the study of gene expression, R.R. Reed and his laboratory have used mutants in Drosophila melanogaster and C. elegans that have defects in olfactory fiuiction. - These studies led to the characterization of olfactory transcription factors, which control the transcription of olfactory receptors. The transcription factor, Olf-1, identified by R. R. Reed, activates a number of olfactory receptor genes. Olf-l is expressed only in olfactory epithelia. It is one of several related, highly conserved transcriptional activators that control the differentiation of olfactory neurons. 

Fujishiro N, Kijima H, Morita H (1984) Impulse frequency and action potential amplitude in labellar chemosensory neurones of Drosophila melanogaster. J Insect Physiol 30 317-325 Gao Q, Chess A (1999) Identification of candidate Drosophila olfactory receptors from genomic DNA sequence. Genomics 60 31-39... 

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