Of antiallergic drugs

The Mechanism of Histamine Release from Mast Cells with Reference to the Action of Antiallergic Drugs... 

Varney VA, Gaga M, Frew AJ, Aber VR, Kay AB, Durham SR Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs. BMJ 1991 302 265-269. 

While antacids and antiallergic drugs interfere with the function of histamines, why do these not interfere with the function of each other ... 

The chromone cromolyn sodium (5-5) was at one time considered the forerunner of a novel class of antiallergic and antiasthmatic drugs that act at one of the earliest stages of the allergic reaction. Detailed experiments, acmally conducted after the dmg s clinical effectiveness had been confirmed, suggested that the compound inhibited the release of mediators of the allergic reaction from mast cells. The dmg is not very active when taken orally and is usually applied topically to the lung by insufflation as its sodium salt. Considerable efforts to uncover additional structurally related mediator release inhibitors have had only limited success. 

Preferential Enrichment was found in the middle of the development of a certain antiallergic drug, suplatast tosilate (ST).9 Whenever the racemic sample of ST was synthesized, the ee value of the solid sample obtained after recrystallization differed, i.e., it was not 0%, but was always distributed in the... 

Ohsawa H, Noike H, Kanai M, et al. Preventive effect of an antiallergic drug, pemirolast potassium, on restenosis after... 

Fluticasone propionate is an antiallergic drug marketed as Flovent . U.S. 4,335,121 (assigned to Glaxo) describes the preparation of the API. Estimate the cost of production of the API. 

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