Antennae Drosophila

Using a specific antibody, Shanbhag and collaborators [34] demonstrated that LUSH is expressed in sensilla trichodea of the Drosophila antennae along with two other putative odorant-binding proteins Obp83a (PBPRP-3, OS-F) and Obp83b (OS-E). When antennal sections of the LUSH-deficient mutant were la-... 

The relationship between central and peripheral oscillators is different in flies and mammals. In mammals, these oscillators form a hierarchy in which the central oscillator, which resides in the suprachiasmatic nucleus (SCN), functions as a master clock that is entrained by photic signals from the eye, and in turn drives subservient peripheral oscillators via humoral signals (Moore et al 1995, Yamazaki et al 2000, Kramer et al 2001, Cheng et al 2002). In contrast, both central and peripheral oscillators operate autonomously and are directly entrainable by light in Drosophila (Plautz et al 1997), thus obviating the need for a hierarchical system. Our results support the concept of independent oscillators in flies since central (sUN ) oscillators are not necessary for olfaction rhythms and local oscillators in antennae appear to be sufficient. 

FIGURE 28-39 Effects of mutations in homeotic genes in Drosophila, (a) Normal head, (b) Homeotic mutant (antennapedia) in which antennae are replaced by legs, (c) Normal body structure, (d) Homeotic mutant (bithorax) in which a segment has developed incorrectly to produce an extra set of wings. 

Vosshall L. B., Amrein H., Morozov P. S., Rzhetsky A. and Axel R. (1999) A spatial map of olfactory receptor expression in the Drosophila antenna. Cell 96, 725-736. Vosshall L. B., Price J. L., Sehgal A., Saez L. and Young M. W. (1994) Block in nuclear localization of period protein by a second clock mutation, timeless. Science 263, 1606-1609. 

Vosshall L. B., Amrein H., Morozov P. S., Rzhetsky A. and Axel R. (1999) A spatial map of olfactory receptor expression in the Drosophila antenna. Cell 96, 725-736. 

Baumann A., Frings S., Godde M., Seifert R. and Kaupp U.B. (1994) Primary structure and functional expression of a Drosophila cyclic nucleotide-gated channel present in eyes and antennae. EMBO J. 13, 5040-5050. 

Like all Diptera, Drosophila has two paired appendages that carry olfactory sensilla (Figure 23.1A) the antennae carry ca. 1200 ORNs and the maxillary... 

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