Odor benzenoids

Benzisothiazole is a very pale yellow solid, m.p. 37°, with an odor of bitter almonds. It is slightly soluble in water, volatile in steam, and very soluble in concentrated acids and in almost all organic solvents. It boils at 220° without appreciable decomposition.3 Few other physical properties or spectroscopic data appear to have been recorded, but the 60 MHz NMR spectrum of a solution in carbon tetrachloride shows a singlet at 8.735, ascribed to the proton on the heterocyclic ring, and a complex band between 7.12 and 8.008 resulting from the benzenoid ring protons.25... 

Floral scents are often complex blends of several compounds. These are mainly fatty-acid derivatives, benzenoids, phenylpropanoids, isoprenoids, nitrogen-and sulfur-containing compounds. Knudsen et al. s (1993) comprehensive review of floral odors reported floral scents with as few as three compounds and as many as several hundred. A study of moth-pollinated flowers from the Nyctaginaceae reported as many as 77 compounds in floral scent and as few as one. Studies that have focussed on identifying the site of volatile production in flowers report that they are produced mostly in the petals. Volatiles are both synthesized and released by the epidermal cells or by special glandular trichomes on the petal surface. Other studies have shown that the odor of pollen is also part of the odor signal. ... 

Classes of chemical compounds having different function groups and odor descriptors, some of which are useful to the flavor or perfume industries were selected for this initial study. For example, alcohols, aldehydes, pyrazines and various benzenoid compounds which have been isolated in the volatiles of cooked meat as reviewed by Hornstein (22) were studied. For each class of chemical compounds literature threshold values obtained only from one laboratory were used in order to prevent errors associated with technique or methodology between laboratories that occur for threshold determinations as discussed by Guadagni al. ) and Powers and Ware (23). 

Benzenoids and heteroaromatics odor intensity was highly correlated to log P. Addition of the HB indicator variable improved this correlation significantly (Table III - eq. 9). 

Three classes of compounds, namely, nitroarenes, polycychc benzenoids, and macrocyclic ketones and lactones, possess musky odors. The latter have been used for the longest time in fragrance formulations. Efficient synthetic methods that can be scaled up are necessary to decrease their cost of production. Muscone (93) [45] and civetone [46], are two of the most important classical sources of musk odors. Muscone (93), the principal musk odorant perfume ingredient from the male musk... 

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