Occlusive mask occlusion effects

The middle cerebral artery occlusion model (MCAO) is commonly used in experimental focal cerebral ischemia. This technique causes hypothalamic injury resulting in hyperthermia, worsening outcome and possibly masking neuroprotective effects. Thus, careful temperature monitoring is needed in those preclinical studies. Recently, Gerriets et al. (10) introduced a new MCAO model that involves intraarterial embolizationusing macrospheres. Unlike the traditional MCAO suture model, this macrosphere model does not result in hyperthermia and yet provides reproducible infarcts. 

After leaving the solution to rest for 24 hours and filtering it, UV exposure was what made it effective Solutions not exposed to UV did not appear to work. The skin was also prepared by UV exposure, and the solution was applied five times, leaving each coat to dry before the next application. Urkov then applied an occlusive mask. This mask allowed the superficial layers to hyperhydrate by blocking transepi-dermal water loss (TEWL). The hyperhydration dissolved the salicylic acid that would have precipitated on the skin without occlusion and could not have penetrated, as only the acids in solution can readily penetrate the skin barrier. He then applied zinc stearate powder (which is antiseptic and anti-inflammatory). The erythema subsided in 5-6 days and exfoliation was superficial. The solution can be kept in the fridge for 10 days. 

Experience of conventional" phenol peels also shows that a small percentage of patients complain of nausea or even vomiting shortly after a deep peel. This nausea and vomiting occur within a few hours after the application of an occlusive mask." The cause-and-effect relationship between these symptoms and excessive phenolemia has not been officially established. 

UnKke trichloroacetic acid (TCA), whose effect is restricted by occlusion, the elfectiveness of phenol is improved by maceration. Stegman proved that applying an occlusive mask allows the phenol to penetrate more deeply and... 

Whichever technique is used instead of the occlusive mask, there is an increased risk of infection, injury, allergies or errors, and a transparent occlusive mask is recommended during the first 24 hours to improve the peel s effectiveness, reduce the need for patient participation in post-peel care and lower the risk of secondary infection. 

---